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- NCIT_C190705 IAO_0000115 "A preparation of donor-derived T-lymphocytes that have been genetically engineered to express a T-cell receptor (TCR) specific for HLA-A*02:01-restricted minor histocompatibility antigen HA-2 (HA2), with potential immunomodulating and antineoplastic activities. Following allogeneic haploidentical hematopoietic cell transplantation (HCT) in HLA-A*02:01 positive patients, allogeneic anti-HA-2 TCR-engineered T-cells TSC-101 specifically recognize and bind to HA-2 expressed on tumor cells. This may lead to cytotoxic T-lymphocyte (CTL)-mediated elimination of tumor cells expressing HA-2. HA-2 is a lineage-specific antigen found on leukemia cells." @default.
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- NCIT_C190705 NCIT_P107 "Allogeneic Anti-HA-2 TCR-engineered T-cells TSC-101" @default.
- NCIT_C190705 NCIT_P108 "Allogeneic Anti-HA-2 TCR-engineered T-cells TSC-101" @default.
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- NCIT_C190705 hasExactSynonym "Allogeneic Anti-HA-2 TCR-engineered T-cells TSC-101" @default.
- NCIT_C190705 hasExactSynonym "Allogeneic T-cell Receptor-engineered T-cells TSC-101" @default.
- NCIT_C190705 hasExactSynonym "HA-2-targeting TCR-T-cells TSC-101" @default.
- NCIT_C190705 hasExactSynonym "T-cell Receptor Engineered Donor T-Cells TSC-101" @default.
- NCIT_C190705 hasExactSynonym "TSC 101" @default.
- NCIT_C190705 hasExactSynonym "TSC-101" @default.
- NCIT_C190705 hasExactSynonym "TSC101" @default.
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- NCIT_C190705 type Class @default.
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- NCIT_C190705 label "Allogeneic Anti-HA-2 TCR-engineered T-cells TSC-101" @default.
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