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- NCIT_C190750 IAO_0000115 "A formulation consisting of a lipid nanoparticle (LNP) encapsulating a messenger RNA (mRNA) encoding the full-length, prefusion stabilized spike (S) protein of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron variant lineages BA.4 and BA.5 (Omicron BA.4/BA.5), with potential immunizing activity against SARS-CoV-2. Upon administration of davesomeran, the LNP binds to the plasma membrane of cells and releases the mRNA into the cells. The mRNA is then translated by ribosomes to produce the SARS-CoV-2 S protein. This may activate both humoral and cellular immune responses which may result in protection against SARS-CoV-2 infection." @default.
- NCIT_C190750 NCIT_NHC0 "C190750" @default.
- NCIT_C190750 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C190750 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C190750 NCIT_P108 "Davesomeran" @default.
- NCIT_C190750 NCIT_P208 "CL1799335" @default.
- NCIT_C190750 NCIT_P210 "2798905-80-1" @default.
- NCIT_C190750 NCIT_P319 "TYF7YW7ENF" @default.
- NCIT_C190750 NCIT_P322 "FDA" @default.
- NCIT_C190750 normalizedInformationContent "100" @default.
- NCIT_C190750 referenceCount "1" @default.
- NCIT_C190750 hasExactSynonym "CX-034476 OMICRON BA.4/BA.5" @default.
- NCIT_C190750 hasExactSynonym "DAVESOMERAN" @default.
- NCIT_C190750 hasExactSynonym "Davesomeran" @default.
- NCIT_C190750 inSubset NCIT_C173381 @default.
- NCIT_C190750 inSubset NCIT_C173383 @default.
- NCIT_C190750 inSubset NCIT_C63923 @default.
- NCIT_C190750 type Class @default.
- NCIT_C190750 isDefinedBy ncit.owl @default.
- NCIT_C190750 label "Davesomeran" @default.
- NCIT_C190750 subClassOf NCIT_C1572 @default.
- NCIT_C190750 subClassOf NCIT_C172787 @default.
- NCIT_C190750 subClassOf NCIT_C173023 @default.
- NCIT_C190750 subClassOf NCIT_C181140 @default.
- NCIT_C190750 subClassOf NCIT_C190750 @default.
- NCIT_C190750 subClassOf NCIT_C1908 @default.
- NCIT_C190750 subClassOf NCIT_C1909 @default.
- NCIT_C190750 subClassOf NCIT_C307 @default.
- NCIT_C190750 subClassOf NCIT_C308 @default.
- NCIT_C190750 subClassOf NCIT_C923 @default.
- NCIT_C190750 subClassOf NCIT_C96404 @default.