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- NCIT_C19078 IAO_0000115 "Conditional (or inducible) gene knock-out. A transgenic technique. A transgenic animal is constructed such that a gene of interest, or chromosome region, is flanked by recombination-signal sites (eg, loxP). The animal is then crossed to one which carries the specific recombinase (eg, cre) under the control of a conditional, or tissue specific, promoter. Upon treatment of an inducer the recombinase is expressed, promoting recombination between the signal sites and the loss of the intervening gene or chromosome region. (NCI/OSP)" @default.
- NCIT_C19078 NCIT_NHC0 "C19078" @default.
- NCIT_C19078 NCIT_P106 "Experimental Model of Disease" @default.
- NCIT_C19078 NCIT_P108 "Transient Gene Knock-Out Model" @default.
- NCIT_C19078 NCIT_P207 "C1519609" @default.
- NCIT_C19078 NCIT_P366 "Transient_Gene_Knock-Out_Model" @default.
- NCIT_C19078 normalizedInformationContent "100" @default.
- NCIT_C19078 referenceCount "1" @default.
- NCIT_C19078 hasExactSynonym "Transient Gene Knock-Out Model" @default.
- NCIT_C19078 type Class @default.
- NCIT_C19078 isDefinedBy ncit.owl @default.
- NCIT_C19078 label "Transient Gene Knock-Out Model" @default.
- NCIT_C19078 subClassOf NCIT_C16866 @default.
- NCIT_C19078 subClassOf NCIT_C17456 @default.
- NCIT_C19078 subClassOf NCIT_C18803 @default.
- NCIT_C19078 subClassOf NCIT_C19078 @default.
- NCIT_C19078 subClassOf NCIT_C19148 @default.
- NCIT_C19078 subClassOf NCIT_C19272 @default.
- NCIT_C19078 subClassOf NCIT_C20181 @default.
- NCIT_C19078 subClassOf NCIT_C71164 @default.
- NCIT_C19078 subClassOf NCIT_C80519 @default.