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- NCIT_C193256 IAO_0000115 "A protein complex composed of 18 complement component 1q (C1q) subcomponent chains: six C1qA, six C1qB and six C1qC. The C1q complex is part of the complement component C1 complex (C1 complex) and undergoes confirmational rearrangement following binding of pentraxins or antigen-antibody complexes that include either immunoglobulin M (IgM) or several IgG molecules. These confirmational changes activate the C1r chains of the C1 complex, which, in turn, cleaves C1s chains of the C1 complex. Following C1s cleavage, the C1 complex can proteolytically activate C2 and C4 and promotes formation of C3-convertase, which cleaves C3 and activates the classical complement pathway." @default.
- NCIT_C193256 NCIT_NHC0 "C193256" @default.
- NCIT_C193256 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C193256 NCIT_P108 "Complement Component C1q" @default.
- NCIT_C193256 NCIT_P322 "CDISC" @default.
- NCIT_C193256 NCIT_P325 "An antigen of the "q" subcomponent of the C1 complement protein complex. It can be considered as an autoantigen and is commonly associated with the autoimmune diseases systemic lupus erythematosus and severe rheumatoid arthritis." @default.
- NCIT_C193256 NCIT_R51 NCIT_C17021 @default.
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- NCIT_C193256 NCIT_R51 NCIT_C20027 @default.
- NCIT_C193256 NCIT_R51 NCIT_C21176 @default.
- NCIT_C193256 NCIT_R51 NCIT_C21523 @default.
- NCIT_C193256 NCIT_R51 NCIT_C26548 @default.
- NCIT_C193256 NCIT_R52 NCIT_C16459 @default.
- NCIT_C193256 NCIT_R52 NCIT_C16725 @default.
- NCIT_C193256 NCIT_R52 NCIT_C17021 @default.
- NCIT_C193256 NCIT_R52 NCIT_C20027 @default.
- NCIT_C193256 NCIT_R52 NCIT_C26548 @default.
- NCIT_C193256 NCIT_R53 NCIT_C17828 @default.
- NCIT_C193256 NCIT_R53 NCIT_C17930 @default.
- NCIT_C193256 NCIT_R53 NCIT_C17937 @default.
- NCIT_C193256 NCIT_R53 NCIT_C18839 @default.
- NCIT_C193256 NCIT_R53 NCIT_C21124 @default.
- NCIT_C193256 NCIT_R53 NCIT_C21519 @default.
- NCIT_C193256 NCIT_R53 NCIT_C41572 @default.
- NCIT_C193256 NCIT_R54 NCIT_C16612 @default.
- NCIT_C193256 NCIT_R54 NCIT_C21518 @default.
- NCIT_C193256 normalizedInformationContent "90.826665450122817" @default.
- NCIT_C193256 referenceCount "4" @default.
- NCIT_C193256 hasExactSynonym "C1q Complex" @default.
- NCIT_C193256 hasExactSynonym "C1q" @default.
- NCIT_C193256 hasExactSynonym "COMPLEMENT C1Q" @default.
- NCIT_C193256 hasExactSynonym "Complement C1q" @default.
- NCIT_C193256 hasExactSynonym "Complement Component C1q Complex" @default.
- NCIT_C193256 hasExactSynonym "Complement Component C1q" @default.
- NCIT_C193256 inSubset NCIT_C181169 @default.
- NCIT_C193256 inSubset NCIT_C61410 @default.
- NCIT_C193256 inSubset NCIT_C66830 @default.
- NCIT_C193256 type Class @default.
- NCIT_C193256 isDefinedBy ncit.owl @default.
- NCIT_C193256 label "Complement Component C1q" @default.
- NCIT_C193256 subClassOf B09b10ddbf7e71f7e97f59c273911c41f @default.
- NCIT_C193256 subClassOf B58d55e06caa833586fc6e491f76ef4ad @default.
- NCIT_C193256 subClassOf B7b7abfcf65c57ca7e0d8aa4e26120af0 @default.
- NCIT_C193256 subClassOf Bd7fb89e8be2b21ac880651948cd34ea0 @default.
- NCIT_C193256 subClassOf NCIT_C17021 @default.
- NCIT_C193256 subClassOf NCIT_C193256 @default.
- NCIT_C193256 subClassOf NCIT_C20027 @default.
- NCIT_C193256 subClassOf NCIT_C21176 @default.
- NCIT_C193256 subClassOf NCIT_C21523 @default.
- NCIT_C193256 subClassOf NCIT_C26548 @default.