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- NCIT_C193463 IAO_0000115 "A recombinant bispecific antibody targeting both the tumor-associated antigen (TAA) CD20 and the T-cell surface antigen CD3, with potential immunomodulating and antineoplastic activities. Upon administration, anti-CD20/CD3 bispecific antibody JS203 binds to both T-cells and CD20-expressing B-lineage tumor cells. The resulting cross-linkage may trigger a potent cytotoxic T-lymphocyte (CTL) response against CD20-expressing tumor B-cells. CD20 is exclusively expressed on B-cells during most stages of B-cell development and is often overexpressed in B-cell malignancies." @default.
- NCIT_C193463 NCIT_A7 NCIT_C38896 @default.
- NCIT_C193463 NCIT_NHC0 "C193463" @default.
- NCIT_C193463 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C193463 NCIT_P108 "Anti-CD20/CD3 Bispecific Antibody JS203" @default.
- NCIT_C193463 NCIT_P322 "GDC" @default.
- NCIT_C193463 NCIT_P399 "811747" @default.
- NCIT_C193463 NCIT_R124 NCIT_C17710 @default.
- NCIT_C193463 NCIT_R124 NCIT_C17828 @default.
- NCIT_C193463 NCIT_R124 NCIT_C18219 @default.
- NCIT_C193463 NCIT_R124 NCIT_C19986 @default.
- NCIT_C193463 NCIT_R124 NCIT_C40474 @default.
- NCIT_C193463 normalizedInformationContent "100" @default.
- NCIT_C193463 referenceCount "1" @default.
- NCIT_C193463 hasExactSynonym "Anti-CD20/Anti-CD3 Bispecific Antibody JS203" @default.
- NCIT_C193463 hasExactSynonym "Anti-CD20/CD3 Bispecific Antibody JS203" @default.
- NCIT_C193463 hasExactSynonym "CD20 x CD3 Bispecific Antibody JS203" @default.
- NCIT_C193463 hasExactSynonym "JS 203" @default.
- NCIT_C193463 hasExactSynonym "JS-203" @default.
- NCIT_C193463 hasExactSynonym "JS203" @default.
- NCIT_C193463 inSubset NCIT_C128784 @default.
- NCIT_C193463 inSubset NCIT_C157711 @default.
- NCIT_C193463 inSubset NCIT_C157712 @default.
- NCIT_C193463 inSubset NCIT_C176424 @default.
- NCIT_C193463 type Class @default.
- NCIT_C193463 isDefinedBy ncit.owl @default.
- NCIT_C193463 label "Anti-CD20/CD3 Bispecific Antibody JS203" @default.
- NCIT_C193463 subClassOf NCIT_C112883 @default.
- NCIT_C193463 subClassOf NCIT_C129821 @default.
- NCIT_C193463 subClassOf NCIT_C129822 @default.
- NCIT_C193463 subClassOf NCIT_C141215 @default.
- NCIT_C193463 subClassOf NCIT_C1454 @default.
- NCIT_C193463 subClassOf NCIT_C163758 @default.
- NCIT_C193463 subClassOf NCIT_C164034 @default.
- NCIT_C193463 subClassOf NCIT_C1908 @default.
- NCIT_C193463 subClassOf NCIT_C1909 @default.
- NCIT_C193463 subClassOf NCIT_C193463 @default.
- NCIT_C193463 subClassOf NCIT_C200711 @default.
- NCIT_C193463 subClassOf NCIT_C201282 @default.
- NCIT_C193463 subClassOf NCIT_C20401 @default.
- NCIT_C193463 subClassOf NCIT_C274 @default.
- NCIT_C193463 subClassOf NCIT_C28227 @default.
- NCIT_C193463 subClassOf NCIT_C307 @default.
- NCIT_C193463 subClassOf NCIT_C308 @default.