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- NCIT_C1968 IAO_0000115 "Any substance that inhibits topoisomerase-II, a topoisomerase that relieves torsional stress in a DNA molecule by cutting both strands of the DNA double helix. A topoisomerase II inhibitor can either stabilize the DNA-protein complex or inhibit the catalytic activity of the enzyme. Inhibition of topoisomerase-II causes DNA damage, inhibition of DNA replication, and apoptosis." @default.
- NCIT_C1968 NCIT_NHC0 "C1968" @default.
- NCIT_C1968 NCIT_P106 "Chemical Viewed Functionally" @default.
- NCIT_C1968 NCIT_P108 "Topoisomerase-II Inhibitor" @default.
- NCIT_C1968 NCIT_P207 "C1519554" @default.
- NCIT_C1968 NCIT_P366 "Topoisomerase-II_Inhibitor" @default.
- NCIT_C1968 NCIT_P368 "CHEBI:50750" @default.
- NCIT_C1968 normalizedInformationContent "51.415923945969531" @default.
- NCIT_C1968 referenceCount "1544" @default.
- NCIT_C1968 hasExactSynonym "Topoisomerase-II Inhibitor" @default.
- NCIT_C1968 hasExactSynonym "Topoisomerase-II Inhibitors" @default.
- NCIT_C1968 type Class @default.
- NCIT_C1968 isDefinedBy ncit.owl @default.
- NCIT_C1968 label "Topoisomerase-II Inhibitor" @default.
- NCIT_C1968 subClassOf NCIT_C129824 @default.
- NCIT_C1968 subClassOf NCIT_C129825 @default.
- NCIT_C1968 subClassOf NCIT_C1748 @default.
- NCIT_C1968 subClassOf NCIT_C1908 @default.
- NCIT_C1968 subClassOf NCIT_C1909 @default.
- NCIT_C1968 subClassOf NCIT_C1968 @default.
- NCIT_C1968 subClassOf NCIT_C2189 @default.
- NCIT_C1968 subClassOf NCIT_C274 @default.
- NCIT_C1968 subClassOf NCIT_C471 @default.