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• NCIT_C19705 IAO_0000115 "Prostaglandin G/H synthase 1 (599 aa, ~69 kDa) is encoded by the human PTGS1 gene. This protein plays a role in vasoconstriction, blood pressure homeostasis and prostaglandin metabolism." @default.
• NCIT_C19705 NCIT_NHC0 "C19705" @default.
• NCIT_C19705 NCIT_P100 "176805" @default.
• NCIT_C19705 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
• NCIT_C19705 NCIT_P106 "Enzyme" @default.
• NCIT_C19705 NCIT_P107 "Prostaglandin G/H Synthase 1" @default.
• NCIT_C19705 NCIT_P108 "Prostaglandin G/H Synthase 1" @default.
• NCIT_C19705 NCIT_P207 "C1565830" @default.
• NCIT_C19705 NCIT_P322 "CTRP" @default.
• NCIT_C19705 NCIT_P366 "Prostaglandin-Endoperoxide_Synthase-1" @default.
• NCIT_C19705 NCIT_P93 "P23219" @default.
• NCIT_C19705 NCIT_P98 "COX-1 is known to be present in most tissues as the housekeeper enzyme, maintains normal gastric mucosa and influences kidney function, while COX-2 is inducible by inflammation. They share 60% homology. The expression of Cox-1 is induced by cytokines and mitogens, hence it is likely to play a role in inflammatory diseases such as rheumatoid arthritis. It contains one EGF-like domain. Both isoforms have the same affinity to convert arachidonic acid to prostaglandin. COX-1. Both forms of COX proteins are membrane associated heme proteins containing cyclooxygenase and peroxidase activities. These enzymes are targets of NSAID (Non steroidal anti-inflammatory drugs) such as aspirin." @default.
• NCIT_C19705 NCIT_R131 NCIT_C18611 @default.
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• NCIT_C19705 NCIT_R131 NCIT_C39235 @default.
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• NCIT_C19705 NCIT_R131 NCIT_C55290 @default.
• NCIT_C19705 NCIT_R131 NCIT_C91821 @default.
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• NCIT_C19705 NCIT_R45 NCIT_C14250 @default.
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• NCIT_C19705 NCIT_R45 NCIT_C14282 @default.
• NCIT_C19705 NCIT_R45 NCIT_C25796 @default.
• NCIT_C19705 NCIT_R45 NCIT_C79740 @default.
• NCIT_C19705 NCIT_R46 NCIT_C12219 @default.
• NCIT_C19705 NCIT_R46 NCIT_C13230 @default.
• NCIT_C19705 NCIT_R46 NCIT_C13269 @default.
• NCIT_C19705 NCIT_R46 NCIT_C13735 @default.
• NCIT_C19705 NCIT_R46 NCIT_C14070 @default.
• NCIT_C19705 NCIT_R46 NCIT_C14135 @default.
• NCIT_C19705 NCIT_R46 NCIT_C32221 @default.
• NCIT_C19705 NCIT_R46 NCIT_C33089 @default.
• NCIT_C19705 NCIT_R46 NCIT_C34070 @default.
• NCIT_C19705 NCIT_R50 NCIT_C12219 @default.
• NCIT_C19705 NCIT_R50 NCIT_C13303 @default.
• NCIT_C19705 NCIT_R50 NCIT_C13379 @default.
• NCIT_C19705 NCIT_R50 NCIT_C13671 @default.
• NCIT_C19705 NCIT_R50 NCIT_C13937 @default.
• NCIT_C19705 NCIT_R50 NCIT_C14073 @default.
• NCIT_C19705 NCIT_R50 NCIT_C14134 @default.
• NCIT_C19705 NCIT_R50 NCIT_C21599 @default.
• NCIT_C19705 NCIT_R53 NCIT_C16945 @default.
• NCIT_C19705 NCIT_R53 NCIT_C17133 @default.
• NCIT_C19705 NCIT_R53 NCIT_C17710 @default.
• NCIT_C19705 NCIT_R53 NCIT_C17828 @default.
• NCIT_C19705 NCIT_R53 NCIT_C17932 @default.
• NCIT_C19705 NCIT_R53 NCIT_C19536 @default.
• NCIT_C19705 NCIT_R53 NCIT_C19899 @default.
• NCIT_C19705 NCIT_R53 NCIT_C20480 @default.
• NCIT_C19705 NCIT_R53 NCIT_C21124 @default.
• NCIT_C19705 NCIT_R53 NCIT_C21128 @default.
• NCIT_C19705 NCIT_R53 NCIT_C21147 @default.
• NCIT_C19705 NCIT_R53 NCIT_C25989 @default.
• NCIT_C19705 NCIT_R53 NCIT_C28498 @default.
• NCIT_C19705 NCIT_R54 NCIT_C16612 @default.
• NCIT_C19705 NCIT_R54 NCIT_C20921 @default.
• NCIT_C19705 NCIT_R54 NCIT_C21281 @default.
• NCIT_C19705 NCIT_R54 NCIT_C25939 @default.
• NCIT_C19705 NCIT_R54 NCIT_C26596 @default.
• NCIT_C19705 normalizedInformationContent "100" @default.
• NCIT_C19705 referenceCount "1" @default.
• NCIT_C19705 hasExactSynonym "COX" @default.
• NCIT_C19705 hasExactSynonym "COX-1" @default.
• NCIT_C19705 hasExactSynonym "COX1" @default.
• NCIT_C19705 hasExactSynonym "COX3" @default.
• NCIT_C19705 hasExactSynonym "Cyclo-Oxygenase-1" @default.
• NCIT_C19705 hasExactSynonym "Cyclooxygenase 3" @default.
• NCIT_C19705 hasExactSynonym "Cyclooxygenase" @default.
• NCIT_C19705 hasExactSynonym "Cyclooxygenase-1" @default.
• NCIT_C19705 hasExactSynonym "EC 1.14.99.1" @default.
• NCIT_C19705 hasExactSynonym "Fatty Acid Cyclooxygenase" @default.
• NCIT_C19705 hasExactSynonym "PGH Synthase 1" @default.
• NCIT_C19705 hasExactSynonym "PGH Synthase" @default.
• NCIT_C19705 hasExactSynonym "PGHS-1" @default.
• NCIT_C19705 hasExactSynonym "PHS 1" @default.
• NCIT_C19705 hasExactSynonym "PHS1" @default.
• NCIT_C19705 hasExactSynonym "PTGS" @default.
• NCIT_C19705 hasExactSynonym "PTGS1" @default.
• NCIT_C19705 hasExactSynonym "Prostaglandin G/H Synthase 1" @default.
• NCIT_C19705 hasExactSynonym "Prostaglandin G/H Synthase and Cyclooxygenase" @default.
• NCIT_C19705 hasExactSynonym "Prostaglandin H2 Synthase 1" @default.
• NCIT_C19705 hasExactSynonym "Prostaglandin H2 Synthase" @default.
• NCIT_C19705 hasExactSynonym "Prostaglandin-Endoperoxide Synthase 1" @default.
• NCIT_C19705 hasExactSynonym "Prostaglandin-Endoperoxide Synthase" @default.
• NCIT_C19705 inSubset NCIT_C116977 @default.
• NCIT_C19705 inSubset NCIT_C142799 @default.
• NCIT_C19705 inSubset NCIT_C142800 @default.
• NCIT_C19705 type Class @default.
• NCIT_C19705 isDefinedBy ncit.owl @default.
• NCIT_C19705 label "Prostaglandin G/H Synthase 1" @default.
• NCIT_C19705 subClassOf NCIT_C16554 @default.
• NCIT_C19705 subClassOf NCIT_C16946 @default.
• NCIT_C19705 subClassOf NCIT_C17015 @default.
• NCIT_C19705 subClassOf NCIT_C17021 @default.
• NCIT_C19705 subClassOf NCIT_C19705 @default.
• NCIT_C19705 subClassOf NCIT_C20027 @default.

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