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- NCIT_C1978 IAO_0000115 "An autologous or allogeneic cell vaccine comprised of tumor cells which have been lethally irradiated and genetically modified to secrete granulocyte-macrophage colony stimulating factor (GM-CSF), a hormone which plays a key role in stimulating the body's immune response to vaccines. GM-CSF may stimulate the body's immune system against tumor cells by attracting and enhancing the activation of antigen-presenting cells (APCs), such as dendritic cells (DCs). This promotes antigen presentation to T-lymphocytes and induces a cytotoxic T-lymphocyte (CTL) response against cells expressing tumor-associated antigens (TAAs)." @default.
- NCIT_C1978 NCIT_NHC0 "C1978" @default.
- NCIT_C1978 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C1978 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1978 NCIT_P107 "GM-CSF-secreting Lethally Irradiated Tumor Cell Vaccine" @default.
- NCIT_C1978 NCIT_P108 "GM-CSF-secreting Lethally Irradiated Tumor Cell Vaccine" @default.
- NCIT_C1978 NCIT_P207 "C1517373" @default.
- NCIT_C1978 NCIT_P322 "CTRP" @default.
- NCIT_C1978 NCIT_P366 "GVAX_Cancer_Vaccine" @default.
- NCIT_C1978 normalizedInformationContent "87.123597049860606" @default.
- NCIT_C1978 referenceCount "7" @default.
- NCIT_C1978 hasExactSynonym "GM-CSF-secreting Lethally Irradiated Tumor Cell Vaccine" @default.
- NCIT_C1978 hasExactSynonym "GVAX Cancer Vaccine" @default.
- NCIT_C1978 hasExactSynonym "GVAX Tumor Vaccine" @default.
- NCIT_C1978 inSubset NCIT_C116977 @default.
- NCIT_C1978 inSubset NCIT_C116978 @default.
- NCIT_C1978 type Class @default.
- NCIT_C1978 isDefinedBy ncit.owl @default.
- NCIT_C1978 label "GM-CSF-secreting Lethally Irradiated Tumor Cell Vaccine" @default.
- NCIT_C1978 subClassOf NCIT_C129820 @default.
- NCIT_C1978 subClassOf NCIT_C142078 @default.
- NCIT_C1978 subClassOf NCIT_C154231 @default.
- NCIT_C1978 subClassOf NCIT_C1663 @default.
- NCIT_C1978 subClassOf NCIT_C1908 @default.
- NCIT_C1978 subClassOf NCIT_C1909 @default.
- NCIT_C1978 subClassOf NCIT_C1962 @default.
- NCIT_C1978 subClassOf NCIT_C1978 @default.
- NCIT_C1978 subClassOf NCIT_C2341 @default.
- NCIT_C1978 subClassOf NCIT_C274 @default.
- NCIT_C1978 subClassOf NCIT_C307 @default.
- NCIT_C1978 subClassOf NCIT_C308 @default.
- NCIT_C1978 subClassOf NCIT_C923 @default.