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- NCIT_C198533 IAO_0000115 "An orally bioavailable androgen receptor (AR) chimeric degrader, with potential antineoplastic activity. Upon aoral dministration, AR degrader AC176 targets and degrades AR, thereby preventing AR-mediated signaling and inhibiting the proliferation of AR-overexpressing tumor cells. AR, a hormone-regulated transcription factor, plays a key role in tumor cell proliferation in castration-resistant prostate cancer (CRPC)." @default.
- NCIT_C198533 NCIT_A7 NCIT_C17063 @default.
- NCIT_C198533 NCIT_NHC0 "C198533" @default.
- NCIT_C198533 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C198533 NCIT_P107 "Androgen Receptor Degrader AC176" @default.
- NCIT_C198533 NCIT_P108 "Androgen Receptor Degrader AC176" @default.
- NCIT_C198533 NCIT_P322 "CTRP" @default.
- NCIT_C198533 NCIT_P322 "GDC" @default.
- NCIT_C198533 NCIT_P399 "812077" @default.
- NCIT_C198533 normalizedInformationContent "100" @default.
- NCIT_C198533 referenceCount "1" @default.
- NCIT_C198533 hasExactSynonym "AC 176" @default.
- NCIT_C198533 hasExactSynonym "AC-176" @default.
- NCIT_C198533 hasExactSynonym "AC0176" @default.
- NCIT_C198533 hasExactSynonym "AC176" @default.
- NCIT_C198533 hasExactSynonym "AR Degrader AC176" @default.
- NCIT_C198533 hasExactSynonym "Androgen Receptor Degrader AC176" @default.
- NCIT_C198533 inSubset NCIT_C116977 @default.
- NCIT_C198533 inSubset NCIT_C116978 @default.
- NCIT_C198533 inSubset NCIT_C128784 @default.
- NCIT_C198533 inSubset NCIT_C157711 @default.
- NCIT_C198533 inSubset NCIT_C157712 @default.
- NCIT_C198533 inSubset NCIT_C176424 @default.
- NCIT_C198533 type Class @default.
- NCIT_C198533 isDefinedBy ncit.owl @default.
- NCIT_C198533 label "Androgen Receptor Degrader AC176" @default.
- NCIT_C198533 subClassOf NCIT_C146993 @default.
- NCIT_C198533 subClassOf NCIT_C147908 @default.
- NCIT_C198533 subClassOf NCIT_C163758 @default.
- NCIT_C198533 subClassOf NCIT_C1908 @default.
- NCIT_C198533 subClassOf NCIT_C1909 @default.
- NCIT_C198533 subClassOf NCIT_C198533 @default.
- NCIT_C198533 subClassOf NCIT_C242 @default.
- NCIT_C198533 subClassOf NCIT_C274 @default.
- NCIT_C198533 subClassOf NCIT_C547 @default.