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- NCIT_C198693 IAO_0000115 "A radioconjugate composed of a nanobody directed against human epidermal growth factor receptor 2 (HER2; EGFR2; ERBB2) that is site-specifically labeled with technetium Tc 99m, with potential use as a tracer for HER2-expressing tumors using single photon emission computed tomography/computed tomography (SPECT/CT). Upon administration of technetium Tc-99m-MIRC213, the anti-HER2 nanobody moiety targets and binds to HER2-expressing tumor cells. This allows the detection of HER2-expressing tumor cells upon SPECT/CT. HER2, a receptor tyrosine kinase, is overexpressed on the cell surfaces of various tumor cell types; it plays a key role in tumor cell proliferation and tumor vascularization." @default.
- NCIT_C198693 NCIT_A7 NCIT_C17319 @default.
- NCIT_C198693 NCIT_NHC0 "C198693" @default.
- NCIT_C198693 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C198693 NCIT_P108 "Technetium Tc-99m-MIRC213" @default.
- NCIT_C198693 NCIT_P399 "812127" @default.
- NCIT_C198693 normalizedInformationContent "100" @default.
- NCIT_C198693 referenceCount "1" @default.
- NCIT_C198693 hasExactSynonym "99mTc-MIRC213" @default.
- NCIT_C198693 hasExactSynonym "Technetium Tc 99m-MIRC213" @default.
- NCIT_C198693 hasExactSynonym "Technetium Tc-99m-MIRC213" @default.
- NCIT_C198693 inSubset NCIT_C176424 @default.
- NCIT_C198693 type Class @default.
- NCIT_C198693 isDefinedBy ncit.owl @default.
- NCIT_C198693 label "Technetium Tc-99m-MIRC213" @default.
- NCIT_C198693 subClassOf NCIT_C1446 @default.
- NCIT_C198693 subClassOf NCIT_C1511 @default.
- NCIT_C198693 subClassOf NCIT_C1512 @default.
- NCIT_C198693 subClassOf NCIT_C1908 @default.
- NCIT_C198693 subClassOf NCIT_C1909 @default.
- NCIT_C198693 subClassOf NCIT_C198693 @default.
- NCIT_C198693 subClassOf NCIT_C2124 @default.
- NCIT_C198693 subClassOf NCIT_C307 @default.
- NCIT_C198693 subClassOf NCIT_C308 @default.