Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C198982> ?p ?o ?g. }
Showing items 1 to 27 of
27
with 100 items per page.
- NCIT_C198982 IAO_0000115 "A radioconjugate composed of bombesin (BBN), a tetra-decapeptide that binds with high affinity to the gastrin-releasing peptide receptor (GRPR), linked by the sarcophagine chelator (SAR) and radiolabeled with the beta-emitting radioisotope copper Cu 67, with potential antineoplastic activity. Upon administration of copper Cu 67 SAR-BBN, the BBN moiety targets and binds to GRPR, thereby delivering a cytotoxic dose of beta radiation to GRPR-expressing tumor cells. GRPR, also called bombesin receptor 2 (BB2), is a seven-transmembrane G protein-coupled receptor belonging to the bombesin receptor family. It is overexpressed in certain types of cancers." @default.
- NCIT_C198982 NCIT_A7 NCIT_C95067 @default.
- NCIT_C198982 NCIT_NHC0 "C198982" @default.
- NCIT_C198982 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C198982 NCIT_P108 "Copper Cu 67 SAR-bombesin" @default.
- NCIT_C198982 NCIT_P322 "GDC" @default.
- NCIT_C198982 NCIT_P399 "812185" @default.
- NCIT_C198982 normalizedInformationContent "100" @default.
- NCIT_C198982 referenceCount "1" @default.
- NCIT_C198982 hasExactSynonym "67Cu-SAR-BBN" @default.
- NCIT_C198982 hasExactSynonym "67Cu-SAR-bombesin" @default.
- NCIT_C198982 hasExactSynonym "Copper Cu 67 SAR-BBN" @default.
- NCIT_C198982 hasExactSynonym "Copper Cu 67 SAR-bombesin" @default.
- NCIT_C198982 inSubset NCIT_C128784 @default.
- NCIT_C198982 inSubset NCIT_C157711 @default.
- NCIT_C198982 inSubset NCIT_C157712 @default.
- NCIT_C198982 inSubset NCIT_C176424 @default.
- NCIT_C198982 type Class @default.
- NCIT_C198982 isDefinedBy ncit.owl @default.
- NCIT_C198982 label "Copper Cu 67 SAR-bombesin" @default.
- NCIT_C198982 subClassOf NCIT_C129819 @default.
- NCIT_C198982 subClassOf NCIT_C1446 @default.
- NCIT_C198982 subClassOf NCIT_C1908 @default.
- NCIT_C198982 subClassOf NCIT_C1909 @default.
- NCIT_C198982 subClassOf NCIT_C198982 @default.
- NCIT_C198982 subClassOf NCIT_C2124 @default.
- NCIT_C198982 subClassOf NCIT_C274 @default.