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- NCIT_C198985 IAO_0000115 "A prolonged-release formulation composed of a suspension of the thalidomide analog lenalidomide coated with slow-dissolving nontoxic inorganic oxides, with potential antineoplastic activity. Upon administration via subcutaneous injection, the coating dissolves and lenalidomide is released. Lenalidomide inhibits tumor necrosis factor alpha (TNF-alpha) production, stimulates T-lymphocytes, reduces serum levels of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF; FGF2), and inhibits angiogenesis. Additionally, lenalidomide promotes G1 cell cycle arrest and induces apoptosis in malignant cells." @default.
- NCIT_C198985 NCIT_NHC0 "C198985" @default.
- NCIT_C198985 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C198985 NCIT_P108 "Lenalidomide Prolonged-release Formulation NEX-20A" @default.
- NCIT_C198985 NCIT_P322 "GDC" @default.
- NCIT_C198985 NCIT_P399 "812187" @default.
- NCIT_C198985 NCIT_R124 NCIT_C17710 @default.
- NCIT_C198985 NCIT_R124 NCIT_C17828 @default.
- NCIT_C198985 NCIT_R124 NCIT_C19986 @default.
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- NCIT_C198985 NCIT_R125 NCIT_C17828 @default.
- NCIT_C198985 NCIT_R125 NCIT_C17932 @default.
- NCIT_C198985 NCIT_R125 NCIT_C20150 @default.
- NCIT_C198985 NCIT_R125 NCIT_C20480 @default.
- NCIT_C198985 NCIT_R125 NCIT_C21124 @default.
- NCIT_C198985 NCIT_R125 NCIT_C21128 @default.
- NCIT_C198985 NCIT_R125 NCIT_C21147 @default.
- NCIT_C198985 NCIT_R125 NCIT_C26044 @default.
- NCIT_C198985 NCIT_R125 NCIT_C40715 @default.
- NCIT_C198985 NCIT_R125 NCIT_C41515 @default.
- NCIT_C198985 NCIT_R125 NCIT_C51037 @default.
- NCIT_C198985 normalizedInformationContent "100" @default.
- NCIT_C198985 referenceCount "1" @default.
- NCIT_C198985 hasExactSynonym "Lenalidomide Long-acting Formulation NEX-20A" @default.
- NCIT_C198985 hasExactSynonym "Lenalidomide Prolonged-release Formulation NEX-20A" @default.
- NCIT_C198985 hasExactSynonym "NEX 20A" @default.
- NCIT_C198985 hasExactSynonym "NEX-20A" @default.
- NCIT_C198985 hasExactSynonym "NEX20A" @default.
- NCIT_C198985 inSubset NCIT_C128784 @default.
- NCIT_C198985 inSubset NCIT_C157711 @default.
- NCIT_C198985 inSubset NCIT_C157712 @default.
- NCIT_C198985 inSubset NCIT_C176424 @default.
- NCIT_C198985 type Class @default.
- NCIT_C198985 isDefinedBy ncit.owl @default.
- NCIT_C198985 label "Lenalidomide Prolonged-release Formulation NEX-20A" @default.
- NCIT_C198985 subClassOf B15142e7f0e62845e3830234333a0e579 @default.
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- NCIT_C198985 subClassOf NCIT_C129820 @default.
- NCIT_C198985 subClassOf NCIT_C157388 @default.
- NCIT_C198985 subClassOf NCIT_C1742 @default.
- NCIT_C198985 subClassOf NCIT_C1908 @default.
- NCIT_C198985 subClassOf NCIT_C1909 @default.
- NCIT_C198985 subClassOf NCIT_C1913 @default.
- NCIT_C198985 subClassOf NCIT_C1915 @default.
- NCIT_C198985 subClassOf NCIT_C1933 @default.
- NCIT_C198985 subClassOf NCIT_C198985 @default.
- NCIT_C198985 subClassOf NCIT_C274 @default.
- NCIT_C198985 subClassOf NCIT_C308 @default.
- NCIT_C198985 subClassOf NCIT_C54677 @default.
- NCIT_C198985 subClassOf NCIT_C718 @default.