Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C198991> ?p ?o ?g. }
Showing items 1 to 35 of
35
with 100 items per page.
- NCIT_C198991 IAO_0000115 "A human monoclonal antibody directed against CD25 (interleukin-2 receptor subunit alpha; IL-2R alpha; IL-2Ra), with potential antineoplastic activity. Upon administration, anti-CD25 monoclonal antibody BA1106 targets and binds to CD25 expressed on tumor-infiltrating regulatory T (Treg) cells. This may deplete Treg cells in the tumor microenvironment (TME) through antibody-dependent cellular cytotoxicity (ADCC) and prevent immunosuppression, thereby increasing the number of effector T (Teff) cells and enhancing anti-tumor immune responses. CD25, the alpha chain of the IL-2 receptor, is highly expressed on Treg cells but not on Teff cells in tumors." @default.
- NCIT_C198991 NCIT_A7 NCIT_C17073 @default.
- NCIT_C198991 NCIT_NHC0 "C198991" @default.
- NCIT_C198991 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C198991 NCIT_P108 "Anti-CD25 Monoclonal Antibody BA1106" @default.
- NCIT_C198991 NCIT_P322 "GDC" @default.
- NCIT_C198991 NCIT_P399 "812179" @default.
- NCIT_C198991 NCIT_R124 NCIT_C17710 @default.
- NCIT_C198991 NCIT_R124 NCIT_C17828 @default.
- NCIT_C198991 NCIT_R124 NCIT_C18219 @default.
- NCIT_C198991 NCIT_R124 NCIT_C19986 @default.
- NCIT_C198991 NCIT_R124 NCIT_C40474 @default.
- NCIT_C198991 normalizedInformationContent "100" @default.
- NCIT_C198991 referenceCount "1" @default.
- NCIT_C198991 hasExactSynonym "Anti-CD25 Monoclonal Antibody BA1106" @default.
- NCIT_C198991 hasExactSynonym "BA 1106" @default.
- NCIT_C198991 hasExactSynonym "BA-1106" @default.
- NCIT_C198991 hasExactSynonym "BA1106" @default.
- NCIT_C198991 inSubset NCIT_C128784 @default.
- NCIT_C198991 inSubset NCIT_C157711 @default.
- NCIT_C198991 inSubset NCIT_C157712 @default.
- NCIT_C198991 inSubset NCIT_C176424 @default.
- NCIT_C198991 type Class @default.
- NCIT_C198991 isDefinedBy ncit.owl @default.
- NCIT_C198991 label "Anti-CD25 Monoclonal Antibody BA1106" @default.
- NCIT_C198991 subClassOf NCIT_C129821 @default.
- NCIT_C198991 subClassOf NCIT_C129822 @default.
- NCIT_C198991 subClassOf NCIT_C1908 @default.
- NCIT_C198991 subClassOf NCIT_C1909 @default.
- NCIT_C198991 subClassOf NCIT_C198991 @default.
- NCIT_C198991 subClassOf NCIT_C20401 @default.
- NCIT_C198991 subClassOf NCIT_C274 @default.
- NCIT_C198991 subClassOf NCIT_C307 @default.
- NCIT_C198991 subClassOf NCIT_C308 @default.
- NCIT_C198991 subClassOf NCIT_C75525 @default.