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- NCIT_C199435 IAO_0000115 "SARS-CoV-2 replicase polyprotein 1ab (7096 aa, ~794 kDa) is encoded by the SARS-CoV-2 ORF1ab gene. This protein is involved in self-proteolysis that yields 15 non-structural viral proteins that replicate and transcribe the viral genome." @default.
- NCIT_C199435 NCIT_NHC0 "C199435" @default.
- NCIT_C199435 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C199435 NCIT_P106 "Enzyme" @default.
- NCIT_C199435 NCIT_P108 "SARS-CoV-2 Replicase Polyprotein 1ab" @default.
- NCIT_C199435 NCIT_P93 "P0DTD1" @default.
- NCIT_C199435 NCIT_P98 "SARS-CoV-2 replicase polyprotein 1ab is self-cleaved to release the following 15 non-structural viral proteins: host translation inhibitor nsp1 (leader protein, non-structural protein 1, nsp1); non-structural protein 2 (nsp2, p65 homolog); papain-like protease nsp3 (non-structural protein 3, nsp3, PL2-PRO, papain-like proteinase, PL-PRO, EC 3.4.19.12, EC 3.4.22.-); non-structural protein 4 (nsp4); 3C-like proteinase nsp5 (3CL-PRO, 3CLp, main protease Mpro, non-structural protein 5, nsp5, SARS coronavirus main proteinase, EC 3.4.22.692); non-structural protein 6 (nsp6); non-structural protein 7 (nsp7); non-structural protein 8 (nsp8); RNA-capping enzyme subunit nsp9 (non-structural protein 9, nsp9, EC 2.7.7.50); non-structural protein 10 (nsp10, growth factor-like peptide, GFL); RNA-directed RNA polymerase nsp12 (Pol, RdRp, non-structural protein 12, nsp12, EC 2.7.7.48); helicase nsp13 (Hel, non-structural protein 13, nsp13, EC 3.6.4.12, EC 3.6.4.13); guanine-N7 methyltransferase nsp14 (non-structural protein 14, nsp14, proofreading exoribonuclease nsp14, ExoN, EC 2.1.1.56, EC 3.1.13.-); uridylate-specific endoribonuclease nsp15 (NendoU, non-structural protein 15, nsp15, EC 4.6.1.-); and 2'-O-methyltransferase nsp16 (non-structural protein 16, nsp16, EC 2.1.1.57). (UniProt)" @default.
- NCIT_C199435 NCIT_R45 NCIT_C14250 @default.
- NCIT_C199435 NCIT_R45 NCIT_C14283 @default.
- NCIT_C199435 NCIT_R54 NCIT_C16612 @default.
- NCIT_C199435 NCIT_R54 NCIT_C16620 @default.
- NCIT_C199435 NCIT_R54 NCIT_C199422 @default.
- NCIT_C199435 NCIT_R54 NCIT_C199434 @default.
- NCIT_C199435 NCIT_R54 NCIT_C20157 @default.
- NCIT_C199435 normalizedInformationContent "100" @default.
- NCIT_C199435 referenceCount "1" @default.
- NCIT_C199435 hasExactSynonym "ORF1ab Polyprotein" @default.
- NCIT_C199435 hasExactSynonym "ORF1ab" @default.
- NCIT_C199435 hasExactSynonym "Replicase Polyprotein 1ab" @default.
- NCIT_C199435 hasExactSynonym "SARS Coronavirus 2 Replicase Polyprotein 1ab" @default.
- NCIT_C199435 hasExactSynonym "SARS-2 Replicase Polyprotein 1ab" @default.
- NCIT_C199435 hasExactSynonym "SARS-CoV-2 Replicase Polyprotein 1ab" @default.
- NCIT_C199435 hasExactSynonym "SARS2 Replicase Polyprotein 1ab" @default.
- NCIT_C199435 hasExactSynonym "Severe Acute Respiratory Syndrome Coronavirus 2 Replicase Polyprotein 1ab" @default.
- NCIT_C199435 hasExactSynonym "pp1ab" @default.
- NCIT_C199435 inSubset NCIT_C173381 @default.
- NCIT_C199435 inSubset NCIT_C177415 @default.
- NCIT_C199435 type Class @default.
- NCIT_C199435 isDefinedBy ncit.owl @default.
- NCIT_C199435 label "SARS-CoV-2 Replicase Polyprotein 1ab" @default.
- NCIT_C199435 subClassOf B52b5c9ca216e16c446d63354f230031e @default.
- NCIT_C199435 subClassOf B6390b62607b372e34e9127534db0b841 @default.
- NCIT_C199435 subClassOf NCIT_C17021 @default.
- NCIT_C199435 subClassOf NCIT_C17254 @default.
- NCIT_C199435 subClassOf NCIT_C199435 @default.
- NCIT_C199435 subClassOf NCIT_C20032 @default.
- NCIT_C199435 subClassOf NCIT_C20158 @default.
- NCIT_C199435 subClassOf NCIT_C26548 @default.