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- NCIT_C19993 IAO_0000115 "The c-SKI proto-oncogene encodes a transcriptional repressor that homo- and heterodimerizes with the related protein, snoN. SMAD3 associates with nuclear SKI protein in response to TGFB1 signaling, repressing transcriptional activation by SMAD3, and rendering cells resistant to the growth-inhibitory effects of TGFB. The effects of SKI can be overcome by increased expression of SMAD3. (from OMIM 164780 and NCI)" @default.
- NCIT_C19993 NCIT_NHC0 "C19993" @default.
- NCIT_C19993 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C19993 NCIT_P106 "Biologically Active Substance" @default.
- NCIT_C19993 NCIT_P108 "SKI Oncoprotein" @default.
- NCIT_C19993 NCIT_P207 "C1335830" @default.
- NCIT_C19993 NCIT_P366 "SKI_Oncoprotein" @default.
- NCIT_C19993 NCIT_R52 NCIT_C16923 @default.
- NCIT_C19993 NCIT_R52 NCIT_C17021 @default.
- NCIT_C19993 NCIT_R52 NCIT_C17207 @default.
- NCIT_C19993 NCIT_R52 NCIT_C18466 @default.
- NCIT_C19993 NCIT_R52 NCIT_C20027 @default.
- NCIT_C19993 NCIT_R52 NCIT_C20030 @default.
- NCIT_C19993 NCIT_R52 NCIT_C26199 @default.
- NCIT_C19993 NCIT_R52 NCIT_C26548 @default.
- NCIT_C19993 NCIT_R53 NCIT_C16956 @default.
- NCIT_C19993 NCIT_R53 NCIT_C17828 @default.
- NCIT_C19993 NCIT_R53 NCIT_C18121 @default.
- NCIT_C19993 NCIT_R53 NCIT_C18264 @default.
- NCIT_C19993 NCIT_R53 NCIT_C21188 @default.
- NCIT_C19993 NCIT_R54 NCIT_C16612 @default.
- NCIT_C19993 NCIT_R54 NCIT_C16936 @default.
- NCIT_C19993 NCIT_R54 NCIT_C18431 @default.
- NCIT_C19993 NCIT_R54 NCIT_C18449 @default.
- NCIT_C19993 NCIT_R54 NCIT_C19540 @default.
- NCIT_C19993 normalizedInformationContent "100" @default.
- NCIT_C19993 referenceCount "1" @default.
- NCIT_C19993 hasExactSynonym "SK Oncogene" @default.
- NCIT_C19993 hasExactSynonym "SKI Oncoprotein" @default.
- NCIT_C19993 hasExactSynonym "v-SKI Protein" @default.
- NCIT_C19993 type Class @default.
- NCIT_C19993 isDefinedBy ncit.owl @default.
- NCIT_C19993 label "SKI Oncoprotein" @default.
- NCIT_C19993 subClassOf B1d91cdd62a5927ec333a18252187673d @default.
- NCIT_C19993 subClassOf B22e501414e619e83eb73fd9ebaa14c39 @default.
- NCIT_C19993 subClassOf B7899fffe7342cd471b973ed5e7f39ef4 @default.
- NCIT_C19993 subClassOf Ba43f88ebe61e1caf18d342ea53855098 @default.
- NCIT_C19993 subClassOf Bd3abde3a090a42568f01e0852249e6fe @default.
- NCIT_C19993 subClassOf Bfae60b41a07f4168c9ee657e13500ac9 @default.
- NCIT_C19993 subClassOf NCIT_C16934 @default.
- NCIT_C19993 subClassOf NCIT_C17021 @default.
- NCIT_C19993 subClassOf NCIT_C19993 @default.
- NCIT_C19993 subClassOf NCIT_C20027 @default.
- NCIT_C19993 subClassOf NCIT_C26548 @default.