Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C200201> ?p ?o ?g. }
Showing items 1 to 40 of
40
with 100 items per page.
- NCIT_C200201 IAO_0000115 "A bispecific antibody targeting both the tumor-associated antigen (TAA) Claudin 6 (CLDN6; CLDN-6) and the T-cell surface antigen CD3, with potential immunostimulating and antineoplastic activities. Upon intravenous administration, anti-CLDN6/CD3 bispecific antibody SAIL66 targets and binds to both CLDN6 expressed on tumor cells and CD3 expressed on T-cells. This activates and redirects cytotoxic T-lymphocytes (CTLs) to CLDN6-expressing tumor cells, which leads to enhanced CTL-mediated killing of CLDN6-expressing tumor cells. CLDN6, a tight-junction protein and embryonic antigen, is expressed on a variety of tumor cells but is not expressed on normal, healthy adult cells." @default.
- NCIT_C200201 NCIT_A7 NCIT_C117145 @default.
- NCIT_C200201 NCIT_NHC0 "C200201" @default.
- NCIT_C200201 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C200201 NCIT_P108 "Anti-CLDN6/CD3 Bispecific Antibody SAIL66" @default.
- NCIT_C200201 NCIT_P322 "GDC" @default.
- NCIT_C200201 NCIT_P399 "812556" @default.
- NCIT_C200201 NCIT_R124 NCIT_C17710 @default.
- NCIT_C200201 NCIT_R124 NCIT_C17828 @default.
- NCIT_C200201 NCIT_R124 NCIT_C18219 @default.
- NCIT_C200201 NCIT_R124 NCIT_C19986 @default.
- NCIT_C200201 NCIT_R124 NCIT_C40474 @default.
- NCIT_C200201 normalizedInformationContent "100" @default.
- NCIT_C200201 referenceCount "1" @default.
- NCIT_C200201 hasExactSynonym "Anti-CLDN6/Anti-CD3 Bispecific Antibody SAIL66" @default.
- NCIT_C200201 hasExactSynonym "Anti-CLDN6/CD3 Bispecific Antibody SAIL66" @default.
- NCIT_C200201 hasExactSynonym "CLDN6 x CD3 Bispecific Antibody SAIL66" @default.
- NCIT_C200201 hasExactSynonym "SAIL 66" @default.
- NCIT_C200201 hasExactSynonym "SAIL-66" @default.
- NCIT_C200201 hasExactSynonym "SAIL66" @default.
- NCIT_C200201 inSubset NCIT_C128784 @default.
- NCIT_C200201 inSubset NCIT_C157711 @default.
- NCIT_C200201 inSubset NCIT_C157712 @default.
- NCIT_C200201 inSubset NCIT_C176424 @default.
- NCIT_C200201 type Class @default.
- NCIT_C200201 isDefinedBy ncit.owl @default.
- NCIT_C200201 label "Anti-CLDN6/CD3 Bispecific Antibody SAIL66" @default.
- NCIT_C200201 subClassOf NCIT_C112883 @default.
- NCIT_C200201 subClassOf NCIT_C129821 @default.
- NCIT_C200201 subClassOf NCIT_C129822 @default.
- NCIT_C200201 subClassOf NCIT_C1454 @default.
- NCIT_C200201 subClassOf NCIT_C1908 @default.
- NCIT_C200201 subClassOf NCIT_C1909 @default.
- NCIT_C200201 subClassOf NCIT_C200201 @default.
- NCIT_C200201 subClassOf NCIT_C201282 @default.
- NCIT_C200201 subClassOf NCIT_C20401 @default.
- NCIT_C200201 subClassOf NCIT_C274 @default.
- NCIT_C200201 subClassOf NCIT_C28227 @default.
- NCIT_C200201 subClassOf NCIT_C307 @default.
- NCIT_C200201 subClassOf NCIT_C308 @default.