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- NCIT_C200210 IAO_0000115 "A topical preparation containing the oil extracted from the seeds of Nigella sativa, also known as black seed or black cumin, with potential antioxidant, anti-inflammatory and immunomodulatory activities. Upon topical administration of Nigella sativa seed oil, the main constituent thymoquinone may stimulate various cytoprotective antioxidant enzymes. Thymoquinone may also exert anti-inflammatory activity by decreasing the production of inflammation mediators, such as tumor necrosis factor (TNF)-alpha, interleukin (IL) 1-beta and IL-6, and inhibiting pro-inflammatory enzymes, including cyclooxygenase (COX). In addition, thymoquinone may modulate the activity of various immune cells such as T-cells, B-cells, macrophages, neutrophils, natural killer (NK) cells, and dendritic cells (DCs). This may decrease the wound healing process time and may reduce radiation dermatitis upon radiation therapy." @default.
- NCIT_C200210 NCIT_NHC0 "C200210" @default.
- NCIT_C200210 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C200210 NCIT_P108 "Topical Nigella sativa Seed Oil" @default.
- NCIT_C200210 NCIT_P399 "812520" @default.
- NCIT_C200210 normalizedInformationContent "100" @default.
- NCIT_C200210 referenceCount "1" @default.
- NCIT_C200210 hasExactSynonym "Topical Black Seed Oil" @default.
- NCIT_C200210 hasExactSynonym "Topical N. sativa Seed Oil" @default.
- NCIT_C200210 hasExactSynonym "Topical Nigella sativa Seed Oil" @default.
- NCIT_C200210 inSubset NCIT_C176424 @default.
- NCIT_C200210 type Class @default.
- NCIT_C200210 isDefinedBy ncit.owl @default.
- NCIT_C200210 label "Topical Nigella sativa Seed Oil" @default.
- NCIT_C200210 subClassOf NCIT_C1908 @default.
- NCIT_C200210 subClassOf NCIT_C1909 @default.
- NCIT_C200210 subClassOf NCIT_C200210 @default.
- NCIT_C200210 subClassOf NCIT_C29629 @default.
- NCIT_C200210 subClassOf NCIT_C29639 @default.