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- NCIT_C200262 IAO_0000115 "A monoclonal antibody directed against the tumor-associated antigen (TAA) disialoganglioside (GD2; GD-2), with potential antineoplastic activity. Upon administration, anti-GD2 monoclonal antibody BCD-245 may induce cytotoxicity in GD2-expressing tumor cells by antibody-dependent cell-mediated cytotoxicity (ADCC). GD2 is overexpressed on the surface of neuroblastoma (NB) cells and by other neuroectoderm-derived neoplasms, while it is minimally expressed on normal cells." @default.
- NCIT_C200262 NCIT_A7 NCIT_C1110 @default.
- NCIT_C200262 NCIT_NHC0 "C200262" @default.
- NCIT_C200262 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C200262 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C200262 NCIT_P108 "Anti-GD2 Monoclonal Antibody BCD-245" @default.
- NCIT_C200262 NCIT_P322 "GDC" @default.
- NCIT_C200262 NCIT_P399 "812779" @default.
- NCIT_C200262 NCIT_R124 NCIT_C17710 @default.
- NCIT_C200262 NCIT_R124 NCIT_C17828 @default.
- NCIT_C200262 NCIT_R124 NCIT_C18219 @default.
- NCIT_C200262 NCIT_R124 NCIT_C19986 @default.
- NCIT_C200262 NCIT_R124 NCIT_C40474 @default.
- NCIT_C200262 normalizedInformationContent "100" @default.
- NCIT_C200262 referenceCount "1" @default.
- NCIT_C200262 hasExactSynonym "Anti-GD-2 Monoclonal Antibody BCD-245" @default.
- NCIT_C200262 hasExactSynonym "Anti-GD2 Monoclonal Antibody BCD-245" @default.
- NCIT_C200262 hasExactSynonym "BCD 245" @default.
- NCIT_C200262 hasExactSynonym "BCD-245" @default.
- NCIT_C200262 hasExactSynonym "BCD245" @default.
- NCIT_C200262 inSubset NCIT_C128784 @default.
- NCIT_C200262 inSubset NCIT_C157711 @default.
- NCIT_C200262 inSubset NCIT_C157712 @default.
- NCIT_C200262 inSubset NCIT_C176424 @default.
- NCIT_C200262 type Class @default.
- NCIT_C200262 isDefinedBy ncit.owl @default.
- NCIT_C200262 label "Anti-GD2 Monoclonal Antibody BCD-245" @default.
- NCIT_C200262 subClassOf NCIT_C129821 @default.
- NCIT_C200262 subClassOf NCIT_C129822 @default.
- NCIT_C200262 subClassOf NCIT_C155653 @default.
- NCIT_C200262 subClassOf NCIT_C163758 @default.
- NCIT_C200262 subClassOf NCIT_C1908 @default.
- NCIT_C200262 subClassOf NCIT_C1909 @default.
- NCIT_C200262 subClassOf NCIT_C200262 @default.
- NCIT_C200262 subClassOf NCIT_C20401 @default.
- NCIT_C200262 subClassOf NCIT_C274 @default.
- NCIT_C200262 subClassOf NCIT_C307 @default.
- NCIT_C200262 subClassOf NCIT_C308 @default.