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- NCIT_C200460 IAO_0000115 "A preparation of autologous T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) B-cell antigen receptor complex-associated protein beta chain (CD79b; B-cell-specific glycoprotein B29), with potential immunostimulating and antineoplastic activities. Upon administration, autologous anti-CD79b CAR-T cells JV-213 target and bind to CD79b-expressing tumor cells, thereby inducing selective toxicity in CD79b-expressing tumor cells. CD79b, a critical receptor for successful B-cell development and part of the B-cell receptor (BCR) signaling complex, is widely expressed in certain subtypes of B-cell lymphomas." @default.
- NCIT_C200460 NCIT_A7 NCIT_C97426 @default.
- NCIT_C200460 NCIT_NHC0 "C200460" @default.
- NCIT_C200460 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C200460 NCIT_P108 "Autologous Anti-CD79b CAR-T Cells JV-213" @default.
- NCIT_C200460 NCIT_P322 "GDC" @default.
- NCIT_C200460 NCIT_P399 "812837" @default.
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- NCIT_C200460 NCIT_R72 NCIT_C104083 @default.
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- NCIT_C200460 normalizedInformationContent "100" @default.
- NCIT_C200460 referenceCount "1" @default.
- NCIT_C200460 hasExactSynonym "Autologous Anti-CD79b CAR-T Cells JV-213" @default.
- NCIT_C200460 hasExactSynonym "Autologous Anti-CD79b-CAR T-cells JV-213" @default.
- NCIT_C200460 hasExactSynonym "Autologous CD79b-targeting CAR T-cells JV-213" @default.
- NCIT_C200460 hasExactSynonym "JV 213" @default.
- NCIT_C200460 hasExactSynonym "JV-213" @default.
- NCIT_C200460 hasExactSynonym "JV213" @default.
- NCIT_C200460 inSubset NCIT_C128784 @default.
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- NCIT_C200460 type Class @default.
- NCIT_C200460 isDefinedBy ncit.owl @default.
- NCIT_C200460 label "Autologous Anti-CD79b CAR-T Cells JV-213" @default.
- NCIT_C200460 subClassOf NCIT_C129820 @default.
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