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- NCIT_C2005 IAO_0000115 "A humanized monoclonal antibody targeting the CD40 antigen with potential antineoplastic activity. CD-40, an integral membrane protein found on the surface of B lymphocytes and member of the tumor necrosis factor receptor super-family, is highly overexpressed on the cell surface of a number of B-cell malignancies. Monoclonal antibody SGN-14 specifically binds to and inhibits CD-40, thereby inhibiting cell proliferation and inducing cell lysis via antibody-dependent cellular cytotoxicity (ADCC) in cells." @default.
- NCIT_C2005 NCIT_A32 NCIT_C1909 @default.
- NCIT_C2005 NCIT_NHC0 "C2005" @default.
- NCIT_C2005 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C2005 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C2005 NCIT_P108 "Monoclonal Antibody SGN-14" @default.
- NCIT_C2005 NCIT_P207 "C1519138" @default.
- NCIT_C2005 NCIT_P322 "GDC" @default.
- NCIT_C2005 NCIT_P366 "SGN-14" @default.
- NCIT_C2005 NCIT_P375 "Monoclonal Antibody SGN-14" @default.
- NCIT_C2005 NCIT_R124 NCIT_C17710 @default.
- NCIT_C2005 NCIT_R124 NCIT_C17828 @default.
- NCIT_C2005 NCIT_R124 NCIT_C18219 @default.
- NCIT_C2005 NCIT_R124 NCIT_C19986 @default.
- NCIT_C2005 NCIT_R124 NCIT_C40474 @default.
- NCIT_C2005 normalizedInformationContent "100" @default.
- NCIT_C2005 referenceCount "1" @default.
- NCIT_C2005 hasExactSynonym "Monoclonal Antibody SGN-14" @default.
- NCIT_C2005 hasExactSynonym "SGN-14" @default.
- NCIT_C2005 inSubset NCIT_C128784 @default.
- NCIT_C2005 inSubset NCIT_C157711 @default.
- NCIT_C2005 inSubset NCIT_C157712 @default.
- NCIT_C2005 inSubset NCIT_C177537 @default.
- NCIT_C2005 type Class @default.
- NCIT_C2005 isDefinedBy ncit.owl @default.
- NCIT_C2005 label "Monoclonal Antibody SGN-14" @default.
- NCIT_C2005 subClassOf NCIT_C129820 @default.
- NCIT_C2005 subClassOf NCIT_C129821 @default.
- NCIT_C2005 subClassOf NCIT_C129822 @default.
- NCIT_C2005 subClassOf NCIT_C133877 @default.
- NCIT_C2005 subClassOf NCIT_C1908 @default.
- NCIT_C2005 subClassOf NCIT_C1909 @default.
- NCIT_C2005 subClassOf NCIT_C191767 @default.
- NCIT_C2005 subClassOf NCIT_C2005 @default.
- NCIT_C2005 subClassOf NCIT_C20401 @default.
- NCIT_C2005 subClassOf NCIT_C274 @default.
- NCIT_C2005 subClassOf NCIT_C307 @default.
- NCIT_C2005 subClassOf NCIT_C308 @default.