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- NCIT_C200561 IAO_0000115 "A recombinant oncolytic herpes simplex virus type 1 (HSV-1), with potential oncolytic and antineoplastic activities. Upon intratumoral or intraperitoneal administration, oncolytic HSV-1 R130 infects and replicates in tumor cells causing viral-mediated tumor cell lysis. The released virus particles, in turn, infect and replicate in neighboring tumor cells. Tumor antigens released from the lysed tumor cells also activate the immune system to induce a tumor-specific systemic immune and cytotoxic T-lymphocyte (CTL) response, thereby killing nearby non-infected tumor cells." @default.
- NCIT_C200561 NCIT_NHC0 "C200561" @default.
- NCIT_C200561 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C200561 NCIT_P106 "Virus" @default.
- NCIT_C200561 NCIT_P108 "Oncolytic HSV-1 R130" @default.
- NCIT_C200561 NCIT_P322 "GDC" @default.
- NCIT_C200561 NCIT_P399 "813001" @default.
- NCIT_C200561 normalizedInformationContent "100" @default.
- NCIT_C200561 referenceCount "1" @default.
- NCIT_C200561 hasExactSynonym "Oncolytic HSV-1 R130" @default.
- NCIT_C200561 hasExactSynonym "R 130" @default.
- NCIT_C200561 hasExactSynonym "R-130" @default.
- NCIT_C200561 hasExactSynonym "R130" @default.
- NCIT_C200561 inSubset NCIT_C128784 @default.
- NCIT_C200561 inSubset NCIT_C157711 @default.
- NCIT_C200561 inSubset NCIT_C157712 @default.
- NCIT_C200561 inSubset NCIT_C176424 @default.
- NCIT_C200561 type Class @default.
- NCIT_C200561 isDefinedBy ncit.owl @default.
- NCIT_C200561 label "Oncolytic HSV-1 R130" @default.
- NCIT_C200561 subClassOf NCIT_C129821 @default.
- NCIT_C200561 subClassOf NCIT_C1908 @default.
- NCIT_C200561 subClassOf NCIT_C1909 @default.
- NCIT_C200561 subClassOf NCIT_C200561 @default.
- NCIT_C200561 subClassOf NCIT_C274 @default.
- NCIT_C200561 subClassOf NCIT_C307 @default.
- NCIT_C200561 subClassOf NCIT_C717 @default.