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- NCIT_C200610 IAO_0000115 "A ribonucleoprotein complex that targets certain nascent proteins to the endoplasmic reticulum (ER) during translation. In eukaryotes, the signal recognition particle complex (SRP) recognizes the N-terminal hydrophobic signal peptide sequence on nascent peptide chains as they emerge from the ribosome. Next, the SRP slows translation and docks the complex of the ribosome and nascent peptide with the SRP receptor and translocon channel that are co-located in the membrane of the ER. Then, the SRP is released and translation elongation resumes." @default.
- NCIT_C200610 NCIT_NHC0 "C200610" @default.
- NCIT_C200610 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C200610 NCIT_P106 "Enzyme" @default.
- NCIT_C200610 NCIT_P108 "Signal Recognition Particle Ribonucleoprotein Complex" @default.
- NCIT_C200610 NCIT_P322 "CDISC" @default.
- NCIT_C200610 NCIT_P325 "An antigen derived from the ribonucleoprotein complex that targets signal peptide-bearing proteins to the prokaryotic plasma membrane or the eukaryotic endoplasmic reticulum membrane for secretion or membrane insertion. It can be considered as an autoantigen and is commonly associated with the autoimmune disease polymyositis." @default.
- NCIT_C200610 NCIT_P98 "Autoantibodies targeting the signal recognition particle are associated with polymyositis." @default.
- NCIT_C200610 NCIT_P98 "In humans, the signal recognition particle is comprised of 6 proteins (SRP-9, -14, -19, -54, -68, and -72) and three 7SL RNA components (RN7SL1, RN7SL2 and RN7SL3)." @default.
- NCIT_C200610 NCIT_R53 NCIT_C17702 @default.
- NCIT_C200610 NCIT_R53 NCIT_C17710 @default.
- NCIT_C200610 NCIT_R53 NCIT_C17828 @default.
- NCIT_C200610 NCIT_R53 NCIT_C18103 @default.
- NCIT_C200610 NCIT_R53 NCIT_C18146 @default.
- NCIT_C200610 NCIT_R53 NCIT_C18966 @default.
- NCIT_C200610 NCIT_R53 NCIT_C19536 @default.
- NCIT_C200610 NCIT_R53 NCIT_C20149 @default.
- NCIT_C200610 NCIT_R53 NCIT_C21049 @default.
- NCIT_C200610 NCIT_R53 NCIT_C21050 @default.
- NCIT_C200610 NCIT_R53 NCIT_C21079 @default.
- NCIT_C200610 NCIT_R53 NCIT_C28498 @default.
- NCIT_C200610 NCIT_R53 NCIT_C29857 @default.
- NCIT_C200610 NCIT_R53 NCIT_C30022 @default.
- NCIT_C200610 normalizedInformationContent "100" @default.
- NCIT_C200610 referenceCount "1" @default.
- NCIT_C200610 hasExactSynonym "SIGNAL RECOGNITION PARTICLE" @default.
- NCIT_C200610 hasExactSynonym "SRP Complex" @default.
- NCIT_C200610 hasExactSynonym "SRP Ribonucleoprotein Complex" @default.
- NCIT_C200610 hasExactSynonym "SRP" @default.
- NCIT_C200610 hasExactSynonym "Signal Recognition Particle Complex" @default.
- NCIT_C200610 hasExactSynonym "Signal Recognition Particle Ribonucleoprotein Complex" @default.
- NCIT_C200610 hasExactSynonym "Signal Recognition Particle" @default.
- NCIT_C200610 inSubset NCIT_C181169 @default.
- NCIT_C200610 inSubset NCIT_C61410 @default.
- NCIT_C200610 inSubset NCIT_C66830 @default.
- NCIT_C200610 type Class @default.
- NCIT_C200610 isDefinedBy ncit.owl @default.
- NCIT_C200610 label "Signal Recognition Particle Ribonucleoprotein Complex" @default.
- NCIT_C200610 subClassOf B3566edac53e8eab6205d6758f2043bc0 @default.
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- NCIT_C200610 subClassOf NCIT_C21176 @default.
- NCIT_C200610 subClassOf NCIT_C26548 @default.
- NCIT_C200610 subClassOf NCIT_C95949 @default.