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- NCIT_C2007 IAO_0000115 "A genetically-engineered, chimeric mouse-human, anti-CD30 monoclonal antibody with potential antineoplastic activity. Brentuximab specifically binds to the receptor CD-30, a member of the tumor necrosis factor receptor super-family, which may be overexpressed on the surfaces of Hodgkin lymphoma cells and anaplastic-large cell lymphoma cells. After binding to CD30, this agent interferes with the G1 phase of the cell cycle, thereby inducing growth arrest and apoptosis in susceptible tumor cell populations." @default.
- NCIT_C2007 NCIT_A32 NCIT_C1909 @default.
- NCIT_C2007 NCIT_A7 NCIT_C38906 @default.
- NCIT_C2007 NCIT_NHC0 "C2007" @default.
- NCIT_C2007 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C2007 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C2007 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2007 NCIT_P107 "Brentuximab" @default.
- NCIT_C2007 NCIT_P108 "Brentuximab" @default.
- NCIT_C2007 NCIT_P175 "731636" @default.
- NCIT_C2007 NCIT_P207 "C1328236" @default.
- NCIT_C2007 NCIT_P210 "775303-41-8" @default.
- NCIT_C2007 NCIT_P319 "C67ORA155P" @default.
- NCIT_C2007 NCIT_P322 "CTRP" @default.
- NCIT_C2007 NCIT_P322 "FDA" @default.
- NCIT_C2007 NCIT_P322 "GDC" @default.
- NCIT_C2007 NCIT_P325 "A monoclonal antibody that binds to cells that have the CD30 antigen on their surface, including Hodgkin disease cells and cells from anaplastic large cell lymphoma, and cutaneous T-cell lymphoma. SGN-30 is being studied in the treatment of cancer. It is a type of monoclonal antibody." @default.
- NCIT_C2007 NCIT_P329 "357600" @default.
- NCIT_C2007 NCIT_P330 "357600" @default.
- NCIT_C2007 NCIT_P366 "SGN-30" @default.
- NCIT_C2007 NCIT_P375 "Brentuximab" @default.
- NCIT_C2007 NCIT_P399 "357600" @default.
- NCIT_C2007 NCIT_R124 NCIT_C17710 @default.
- NCIT_C2007 NCIT_R124 NCIT_C17828 @default.
- NCIT_C2007 NCIT_R124 NCIT_C18219 @default.
- NCIT_C2007 NCIT_R124 NCIT_C19986 @default.
- NCIT_C2007 NCIT_R124 NCIT_C40474 @default.
- NCIT_C2007 normalizedInformationContent "100" @default.
- NCIT_C2007 referenceCount "1" @default.
- NCIT_C2007 hasExactSynonym "Anti-CD30 Monoclonal Antibody" @default.
- NCIT_C2007 hasExactSynonym "BRENTUXIMAB" @default.
- NCIT_C2007 hasExactSynonym "Brentuximab" @default.
- NCIT_C2007 hasExactSynonym "CAC-10" @default.
- NCIT_C2007 hasExactSynonym "CAC10" @default.
- NCIT_C2007 hasExactSynonym "Monoclonal Antibody SGN-30" @default.
- NCIT_C2007 hasExactSynonym "SGN-30" @default.
- NCIT_C2007 hasExactSynonym "SGN30" @default.
- NCIT_C2007 inSubset NCIT_C116977 @default.
- NCIT_C2007 inSubset NCIT_C116978 @default.
- NCIT_C2007 inSubset NCIT_C128784 @default.
- NCIT_C2007 inSubset NCIT_C157711 @default.
- NCIT_C2007 inSubset NCIT_C157712 @default.
- NCIT_C2007 inSubset NCIT_C176424 @default.
- NCIT_C2007 inSubset NCIT_C177537 @default.
- NCIT_C2007 inSubset NCIT_C63923 @default.
- NCIT_C2007 type Class @default.
- NCIT_C2007 isDefinedBy ncit.owl @default.
- NCIT_C2007 label "Brentuximab" @default.
- NCIT_C2007 subClassOf NCIT_C129821 @default.
- NCIT_C2007 subClassOf NCIT_C129822 @default.
- NCIT_C2007 subClassOf NCIT_C163758 @default.
- NCIT_C2007 subClassOf NCIT_C164002 @default.
- NCIT_C2007 subClassOf NCIT_C164005 @default.
- NCIT_C2007 subClassOf NCIT_C1908 @default.
- NCIT_C2007 subClassOf NCIT_C1909 @default.
- NCIT_C2007 subClassOf NCIT_C2007 @default.
- NCIT_C2007 subClassOf NCIT_C20401 @default.
- NCIT_C2007 subClassOf NCIT_C274 @default.
- NCIT_C2007 subClassOf NCIT_C307 @default.
- NCIT_C2007 subClassOf NCIT_C308 @default.