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- NCIT_C201279 IAO_0000115 "The most abundant immunoglobulin G (IgG) subclass in the circulation of healthy individuals. The IgG1 core hinge sequence contains 15 amino acids and two interchain disulfide bonds. This subtype has high affinity for binding both Fc receptors and complement component C1q. IgG1 is the predominant antibody subclass that responds to antigens derived from both soluble and membrane proteins. Reduced levels of circulating IgG1 can indicate the presence of a variety of primary and secondary antibody deficiencies, which can result in hypogammaglobulinemia." @default.
- NCIT_C201279 NCIT_NHC0 "C201279" @default.
- NCIT_C201279 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C201279 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C201279 NCIT_P108 "IgG1" @default.
- NCIT_C201279 NCIT_P171 "25368619" @default.
- NCIT_C201279 NCIT_R44 NCIT_C21176 @default.
- NCIT_C201279 NCIT_R44 NCIT_C26548 @default.
- NCIT_C201279 NCIT_R52 NCIT_C16295 @default.
- NCIT_C201279 NCIT_R52 NCIT_C16725 @default.
- NCIT_C201279 NCIT_R52 NCIT_C17021 @default.
- NCIT_C201279 NCIT_R52 NCIT_C20027 @default.
- NCIT_C201279 NCIT_R52 NCIT_C26548 @default.
- NCIT_C201279 NCIT_R53 NCIT_C17710 @default.
- NCIT_C201279 NCIT_R53 NCIT_C17828 @default.
- NCIT_C201279 NCIT_R53 NCIT_C17930 @default.
- NCIT_C201279 NCIT_R53 NCIT_C17937 @default.
- NCIT_C201279 NCIT_R53 NCIT_C18219 @default.
- NCIT_C201279 NCIT_R53 NCIT_C18839 @default.
- NCIT_C201279 NCIT_R53 NCIT_C19986 @default.
- NCIT_C201279 NCIT_R53 NCIT_C21124 @default.
- NCIT_C201279 NCIT_R53 NCIT_C40474 @default.
- NCIT_C201279 NCIT_R54 NCIT_C16612 @default.
- NCIT_C201279 NCIT_R54 NCIT_C25790 @default.
- NCIT_C201279 normalizedInformationContent "100" @default.
- NCIT_C201279 referenceCount "1" @default.
- NCIT_C201279 hasExactSynonym "IgG1" @default.
- NCIT_C201279 hasExactSynonym "Immunoglobulin G Subclass 1" @default.
- NCIT_C201279 hasExactSynonym "Immunoglobulin G1" @default.
- NCIT_C201279 type Class @default.
- NCIT_C201279 isDefinedBy ncit.owl @default.
- NCIT_C201279 label "IgG1" @default.
- NCIT_C201279 subClassOf NCIT_C16295 @default.
- NCIT_C201279 subClassOf NCIT_C16725 @default.
- NCIT_C201279 subClassOf NCIT_C17021 @default.
- NCIT_C201279 subClassOf NCIT_C20027 @default.
- NCIT_C201279 subClassOf NCIT_C201279 @default.
- NCIT_C201279 subClassOf NCIT_C26548 @default.
- NCIT_C201279 subClassOf NCIT_C568 @default.
- NCIT_C201279 subClassOf NCIT_C572 @default.