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- NCIT_C201295 IAO_0000115 "A preparation of allogeneic, off-the-shelf (OTS), universal, gene-edited T-lymphocytes expressing a fourth-generation chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) CD7, with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic anti-CD7 CAR T cells 4SCAR7U specifically target and kill CD7-expressing tumor cells. CD7 is a transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. It is expressed in the majority of lymphoblastic T-cell leukemias and lymphomas and in a subset of peripheral T-cell lymphomas." @default.
- NCIT_C201295 NCIT_A7 NCIT_C38935 @default.
- NCIT_C201295 NCIT_NHC0 "C201295" @default.
- NCIT_C201295 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C201295 NCIT_P108 "Allogeneic Anti-CD7 CAR T Cells 4SCAR7U" @default.
- NCIT_C201295 NCIT_P322 "GDC" @default.
- NCIT_C201295 NCIT_P399 "813603" @default.
- NCIT_C201295 normalizedInformationContent "100" @default.
- NCIT_C201295 referenceCount "1" @default.
- NCIT_C201295 hasExactSynonym "4SCAR7U T Cells" @default.
- NCIT_C201295 hasExactSynonym "4SCAR7U" @default.
- NCIT_C201295 hasExactSynonym "Allogeneic Anti-CD7 4SCAR-expressing T-cells 4SCAR7U" @default.
- NCIT_C201295 hasExactSynonym "Allogeneic Anti-CD7 CAR T Cells 4SCAR7U" @default.
- NCIT_C201295 hasExactSynonym "Allogeneic Anti-CD7 CAR T-cells 4SCAR7U" @default.
- NCIT_C201295 hasExactSynonym "Allogeneic Anti-CD7 CAR-T Cells 4SCAR7U" @default.
- NCIT_C201295 hasExactSynonym "Allogeneic CD7-targeting Universal CAR T Cells 4SCAR7U" @default.
- NCIT_C201295 hasExactSynonym "Universal CD7-specific CAR Gene-engineered T Cells 4SCAR7U" @default.
- NCIT_C201295 inSubset NCIT_C128784 @default.
- NCIT_C201295 inSubset NCIT_C157711 @default.
- NCIT_C201295 inSubset NCIT_C157712 @default.
- NCIT_C201295 inSubset NCIT_C176424 @default.
- NCIT_C201295 type Class @default.
- NCIT_C201295 isDefinedBy ncit.owl @default.
- NCIT_C201295 label "Allogeneic Anti-CD7 CAR T Cells 4SCAR7U" @default.
- NCIT_C201295 subClassOf NCIT_C129820 @default.
- NCIT_C201295 subClassOf NCIT_C129821 @default.
- NCIT_C201295 subClassOf NCIT_C129826 @default.
- NCIT_C201295 subClassOf NCIT_C137999 @default.
- NCIT_C201295 subClassOf NCIT_C142078 @default.
- NCIT_C201295 subClassOf NCIT_C154231 @default.
- NCIT_C201295 subClassOf NCIT_C1908 @default.
- NCIT_C201295 subClassOf NCIT_C1909 @default.
- NCIT_C201295 subClassOf NCIT_C1962 @default.
- NCIT_C201295 subClassOf NCIT_C200765 @default.
- NCIT_C201295 subClassOf NCIT_C201177 @default.
- NCIT_C201295 subClassOf NCIT_C201295 @default.
- NCIT_C201295 subClassOf NCIT_C274 @default.
- NCIT_C201295 subClassOf NCIT_C28676 @default.
- NCIT_C201295 subClassOf NCIT_C307 @default.
- NCIT_C201295 subClassOf NCIT_C308 @default.