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- NCIT_C2015 IAO_0000115 "A synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth." @default.
- NCIT_C2015 NCIT_A32 NCIT_C1909 @default.
- NCIT_C2015 NCIT_A7 NCIT_C38910 @default.
- NCIT_C2015 NCIT_NHC0 "C2015" @default.
- NCIT_C2015 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C2015 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2015 NCIT_P107 "Abarelix" @default.
- NCIT_C2015 NCIT_P108 "Abarelix" @default.
- NCIT_C2015 NCIT_P207 "C1174732" @default.
- NCIT_C2015 NCIT_P210 "183552-38-7" @default.
- NCIT_C2015 NCIT_P302 "Prostate Cancer" @default.
- NCIT_C2015 NCIT_P319 "W486SJ5824" @default.
- NCIT_C2015 NCIT_P322 "CTRP" @default.
- NCIT_C2015 NCIT_P322 "FDA" @default.
- NCIT_C2015 NCIT_P322 "GDC" @default.
- NCIT_C2015 NCIT_P325 "A drug used to reduce the amount of testosterone made in patients with advanced symptomatic prostate cancer for which no other treatment options are available. It belongs to the family of drugs called gonadotropin-releasing hormone (GnRH) antagonists." @default.
- NCIT_C2015 NCIT_P329 "415570" @default.
- NCIT_C2015 NCIT_P330 "415570" @default.
- NCIT_C2015 NCIT_P350 "C72H95ClN14O14" @default.
- NCIT_C2015 NCIT_P366 "Abarelix" @default.
- NCIT_C2015 NCIT_P368 "CHEBI:337298" @default.
- NCIT_C2015 NCIT_P375 "Abarelix" @default.
- NCIT_C2015 NCIT_P399 "415570" @default.
- NCIT_C2015 normalizedInformationContent "100" @default.
- NCIT_C2015 referenceCount "1" @default.
- NCIT_C2015 hasExactSynonym "ABARELIX" @default.
- NCIT_C2015 hasExactSynonym "Abarelix" @default.
- NCIT_C2015 hasExactSynonym "PPI-149" @default.
- NCIT_C2015 hasExactSynonym "Plenaxis" @default.
- NCIT_C2015 hasExactSynonym "R-3827" @default.
- NCIT_C2015 hasExactSynonym "abarelix" @default.
- NCIT_C2015 inSubset NCIT_C116977 @default.
- NCIT_C2015 inSubset NCIT_C116978 @default.
- NCIT_C2015 inSubset NCIT_C128784 @default.
- NCIT_C2015 inSubset NCIT_C157711 @default.
- NCIT_C2015 inSubset NCIT_C157712 @default.
- NCIT_C2015 inSubset NCIT_C176424 @default.
- NCIT_C2015 inSubset NCIT_C177537 @default.
- NCIT_C2015 inSubset NCIT_C63923 @default.
- NCIT_C2015 type Class @default.
- NCIT_C2015 isDefinedBy ncit.owl @default.
- NCIT_C2015 label "Abarelix" @default.
- NCIT_C2015 subClassOf NCIT_C147908 @default.
- NCIT_C2015 subClassOf NCIT_C1908 @default.
- NCIT_C2015 subClassOf NCIT_C1909 @default.
- NCIT_C2015 subClassOf NCIT_C2015 @default.
- NCIT_C2015 subClassOf NCIT_C2092 @default.
- NCIT_C2015 subClassOf NCIT_C547 @default.