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- NCIT_C2021 IAO_0000115 "Any substance that inhibits thymidylate synthase, an enzyme that catalyzes the conversion of uridine monophosphate to thymidine monophosphate, the rate-limiting step in de novo production of dTMP. Inhibition of thymidylate synthase causes inhibition of DNA synthesis and cell proloferation." @default.
- NCIT_C2021 NCIT_NHC0 "C2021" @default.
- NCIT_C2021 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2021 NCIT_P108 "Thymidylate Synthase Inhibitor" @default.
- NCIT_C2021 NCIT_P207 "C1373008" @default.
- NCIT_C2021 NCIT_P325 "A drug that blocks DNA synthesis and may prevent tumor cell growth. It is being studied as a treatment for cancer." @default.
- NCIT_C2021 NCIT_P366 "Thymidylate_Synthase_Inhibitor" @default.
- NCIT_C2021 NCIT_P368 "CHEBI:63720" @default.
- NCIT_C2021 normalizedInformationContent "59.385664962611898" @default.
- NCIT_C2021 referenceCount "463" @default.
- NCIT_C2021 hasExactSynonym "Thymidylate Synthase Inhibitor" @default.
- NCIT_C2021 hasExactSynonym "Thymidylate Synthetase Inhibitors" @default.
- NCIT_C2021 hasExactSynonym "thymidylate synthase inhibitor" @default.
- NCIT_C2021 type Class @default.
- NCIT_C2021 isDefinedBy ncit.owl @default.
- NCIT_C2021 label "Thymidylate Synthase Inhibitor" @default.
- NCIT_C2021 subClassOf NCIT_C1908 @default.
- NCIT_C2021 subClassOf NCIT_C1909 @default.
- NCIT_C2021 subClassOf NCIT_C2021 @default.
- NCIT_C2021 subClassOf NCIT_C471 @default.