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- NCIT_C20710 IAO_0000115 "RNA polymerase II transcription of Class II genes involves the TFIID transcription complex comprised of general factors, including TBP, TFIIA, TFIIB, TFIIE, TFIIF, TFIIG/J, and TFIIH, as well as gene-specific factors that include TAFs, which interact with regulatory protein activation domains to enhance transcription. A second group of cofactors includes PC1, PC2, and PC3, which have a strong positive influence on transcription. A third group of factors suppress transcription. The combined action of general and gene-specific regulators encoded by transcription coactivator genes determines appropriate gene expression. (NCI)" @default.
- NCIT_C20710 NCIT_NHC0 "C20710" @default.
- NCIT_C20710 NCIT_P106 "Gene or Genome" @default.
- NCIT_C20710 NCIT_P108 "Transcription Coregulator Gene" @default.
- NCIT_C20710 NCIT_P207 "C1336778" @default.
- NCIT_C20710 NCIT_P366 "Transcription_Coregulator_Gene" @default.
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- NCIT_C20710 NCIT_R37 NCIT_C28498 @default.
- NCIT_C20710 NCIT_R41 NCIT_C14182 @default.
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- NCIT_C20710 NCIT_R41 NCIT_C14234 @default.
- NCIT_C20710 NCIT_R41 NCIT_C14250 @default.
- NCIT_C20710 NCIT_R41 NCIT_C14262 @default.
- NCIT_C20710 NCIT_R41 NCIT_C14282 @default.
- NCIT_C20710 NCIT_R41 NCIT_C25796 @default.
- NCIT_C20710 NCIT_R41 NCIT_C79740 @default.
- NCIT_C20710 normalizedInformationContent "59.133284969470274" @default.
- NCIT_C20710 referenceCount "481" @default.
- NCIT_C20710 hasExactSynonym "Transcription Coactivator/Corepressor Gene" @default.
- NCIT_C20710 hasExactSynonym "Transcription Coregulator Gene" @default.
- NCIT_C20710 hasExactSynonym "Transcriptional Coregulator Gene" @default.
- NCIT_C20710 type Class @default.
- NCIT_C20710 isDefinedBy ncit.owl @default.
- NCIT_C20710 label "Transcription Coregulator Gene" @default.
- NCIT_C20710 subClassOf B431e6e6f79c7762ff1502b759efeda1a @default.
- NCIT_C20710 subClassOf Bf4f3d47b8540747706aafcad1d133b1c @default.
- NCIT_C20710 subClassOf NCIT_C16612 @default.
- NCIT_C20710 subClassOf NCIT_C20710 @default.
- NCIT_C20710 subClassOf NCIT_C54362 @default.