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- NCIT_C20811 IAO_0000115 "Platelet factor 4 (101 aa, ~11 kDa) is encoded by the human PF4 gene. This protein is involved in the negative regulation of endothelial cell proliferation, the chemotaxis of neutrophils and monocytes and the positive regulation of blood coagulation." @default.
- NCIT_C20811 NCIT_NHC0 "C20811" @default.
- NCIT_C20811 NCIT_P100 "173460" @default.
- NCIT_C20811 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C20811 NCIT_P107 "Platelet Factor 4" @default.
- NCIT_C20811 NCIT_P108 "Platelet Factor 4" @default.
- NCIT_C20811 NCIT_P207 "C0032183" @default.
- NCIT_C20811 NCIT_P322 "CTRP" @default.
- NCIT_C20811 NCIT_P366 "Platelet_Factor-4" @default.
- NCIT_C20811 NCIT_P93 "P02776" @default.
- NCIT_C20811 NCIT_P98 "Platelet factor 4 is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its heparin-binding ability causes the neutralization of heparin-like molecules on the endothelial surface of blood vessels, which leads to the inhibition of local antithrombin III activity and promotes coagulation. PF4 is a strong chemoattractant for neutrophils and fibroblasts, which indicates a potential role in inflammation and wound repair. (OMIM)" @default.
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- NCIT_C20811 normalizedInformationContent "100" @default.
- NCIT_C20811 referenceCount "1" @default.
- NCIT_C20811 hasExactSynonym "C-X-C Motif Chemokine 4" @default.
- NCIT_C20811 hasExactSynonym "CXCL4" @default.
- NCIT_C20811 hasExactSynonym "Chemokine (C-X-C motif) Ligand 4" @default.
- NCIT_C20811 hasExactSynonym "Iroplact" @default.
- NCIT_C20811 hasExactSynonym "Oncostatin-A" @default.
- NCIT_C20811 hasExactSynonym "PF4" @default.
- NCIT_C20811 hasExactSynonym "Platelet Factor 4" @default.
- NCIT_C20811 hasExactSynonym "Platelet Factor-4" @default.
- NCIT_C20811 hasExactSynonym "Small Inducible Cytokine B4" @default.
- NCIT_C20811 hasExactSynonym "Small Inducible Cytokine Subfamily B, Member 4" @default.
- NCIT_C20811 hasExactSynonym "Small-Inducible Cytokine B4" @default.
- NCIT_C20811 inSubset NCIT_C116977 @default.
- NCIT_C20811 inSubset NCIT_C142799 @default.
- NCIT_C20811 inSubset NCIT_C142800 @default.
- NCIT_C20811 type Class @default.
- NCIT_C20811 isDefinedBy ncit.owl @default.
- NCIT_C20811 label "Platelet Factor 4" @default.
- NCIT_C20811 subClassOf NCIT_C17021 @default.
- NCIT_C20811 subClassOf NCIT_C20027 @default.
- NCIT_C20811 subClassOf NCIT_C20464 @default.
- NCIT_C20811 subClassOf NCIT_C20466 @default.
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