Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C20946> ?p ?o ?g. }
- NCIT_C20946 IAO_0000115 "Baculoviral IAP repeat-containing protein 3 (604 aa, ~68 kDa) is encoded by the human BIRC3 gene. This protein is involved in the inhibition of apoptosis." @default.
- NCIT_C20946 NCIT_NHC0 "C20946" @default.
- NCIT_C20946 NCIT_P100 "601721" @default.
- NCIT_C20946 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C20946 NCIT_P106 "Enzyme" @default.
- NCIT_C20946 NCIT_P107 "Baculoviral IAP Repeat-Containing Protein 3" @default.
- NCIT_C20946 NCIT_P108 "Baculoviral IAP Repeat-Containing Protein 3" @default.
- NCIT_C20946 NCIT_P207 "C0763658" @default.
- NCIT_C20946 NCIT_P322 "CTRP" @default.
- NCIT_C20946 NCIT_P366 "Baculoviral_IAP_Repeat-Containing_Protein-3" @default.
- NCIT_C20946 NCIT_P93 "Q13489" @default.
- NCIT_C20946 NCIT_P98 "Encoded by BIRC3 Gene (IAP Family) Baculoviral IAP Repeat-Containing Protein 3 inhibits apoptosis by binding to TNF Receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. BIRC3 inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring-type zinc finger domain while the Zn binding domain is involved in protein-protein interactions in caspase inhibition and spindle assembly. BIRC3 is present in many fetal and adult tissues and mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes." @default.
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- NCIT_C20946 normalizedInformationContent "100" @default.
- NCIT_C20946 referenceCount "1" @default.
- NCIT_C20946 hasExactSynonym "API2" @default.
- NCIT_C20946 hasExactSynonym "Apoptosis Inhibitor 2" @default.
- NCIT_C20946 hasExactSynonym "BIRC3" @default.
- NCIT_C20946 hasExactSynonym "Baculoviral IAP Repeat-Containing Protein 3" @default.
- NCIT_C20946 hasExactSynonym "C-IAP2" @default.
- NCIT_C20946 hasExactSynonym "Cellular Inhibitor of Apoptosis-2" @default.
- NCIT_C20946 hasExactSynonym "EC 2.3.2.27" @default.
- NCIT_C20946 hasExactSynonym "Human Inhibitor of Apoptosis Protein-1" @default.
- NCIT_C20946 hasExactSynonym "IAP Homolog C" @default.
- NCIT_C20946 hasExactSynonym "Inhibitor Of Apoptosis Protein 1" @default.
- NCIT_C20946 hasExactSynonym "Inhibitor ff Apoptosis Protein 1" @default.
- NCIT_C20946 hasExactSynonym "Mammalian IAP Homolog C" @default.
- NCIT_C20946 hasExactSynonym "RING Finger Protein 49" @default.
- NCIT_C20946 hasExactSynonym "RING-Type E3 Ubiquitin Transferase BIRC3" @default.
- NCIT_C20946 hasExactSynonym "TNFR2-TRAF Signaling Complex Protein" @default.
- NCIT_C20946 hasExactSynonym "TNFR2-TRAF-Signaling Complex Protein 1" @default.
- NCIT_C20946 hasExactSynonym "hIAP-1" @default.
- NCIT_C20946 hasExactSynonym "hIAP1" @default.
- NCIT_C20946 inSubset NCIT_C116977 @default.
- NCIT_C20946 inSubset NCIT_C142799 @default.
- NCIT_C20946 inSubset NCIT_C142800 @default.
- NCIT_C20946 type Class @default.