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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C21285> ?p ?o ?g. }

• NCIT_C21285 IAO_0000115 "Alpha-1A adrenergic receptor (466 aa, ~51 kDa) is encoded by the human ADRA1A gene. This protein is involved in smooth muscle contraction, cell proliferation, apoptosis and signal transduction." @default.
• NCIT_C21285 NCIT_NHC0 "C21285" @default.
• NCIT_C21285 NCIT_P100 "104221" @default.
• NCIT_C21285 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
• NCIT_C21285 NCIT_P106 "Receptor" @default.
• NCIT_C21285 NCIT_P108 "Alpha-1A Adrenergic Receptor" @default.
• NCIT_C21285 NCIT_P207 "C2932393" @default.
• NCIT_C21285 NCIT_P366 "Alpha-1A_Adrenergic_Receptor" @default.
• NCIT_C21285 NCIT_P93 "P35348" @default.
• NCIT_C21285 NCIT_P98 "Alpha-1A-adrenergic receptor, encoded by the ADRA1A gene, regulates smooth muscle contraction, cellular growth and apoptosis. Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This alpha-adrenergic receptor mediates its action by association with g proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(Q) and G(11) proteins. Alternative splicing of the ADRA1A gene generates 4 transcript variants, which encode 4 different isoforms with distinct C termini but having similar ligand binding properties. Its carboxyl-terminal SER or THR residues may be phosphorylated. (From LocusLink, Swiss_Prot and NCI)" @default.
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• NCIT_C21285 normalizedInformationContent "100" @default.
• NCIT_C21285 referenceCount "1" @default.
• NCIT_C21285 hasExactSynonym "ADRA1A" @default.
• NCIT_C21285 hasExactSynonym "ADRA1C" @default.
• NCIT_C21285 hasExactSynonym "ADRA1L1" @default.
• NCIT_C21285 hasExactSynonym "Adrenergic, Alpha-1A-, Receptor" @default.
• NCIT_C21285 hasExactSynonym "Adrenergic, Alpha-1C-, Receptor" @default.
• NCIT_C21285 hasExactSynonym "Alpha 1A-Adrenoceptor" @default.
• NCIT_C21285 hasExactSynonym "Alpha-1A Adrenergic Receptor" @default.

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