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- NCIT_C21292 IAO_0000115 "Expressed in effector tissues innervated by postganglionic sympathetic adrenergic fibers, Beta Adrenergic Receptor Genes encode Beta Adrenergic Receptors, one of two major classes of adrenergic receptors (alpha and beta) based on their reactions to norepinephrine and epinephrine, on cellular effects of receptor activation, and on relative affinities and reactions to synthetic blocking or stimulating agents. Beta-adrenergic receptors respond to blocking agents such as propranolol and to activating agents such as isoproterenol. Beta-1 type receptors mediate lipolysis and increase cardiac rate and force of contraction; beta-2 type receptor activation promotes bronchial and vascular smooth muscle relaxation. When coupled to adenylate cyclase through Gs protein, Beta Adrenergic Receptor stimulation results in increased intracellular cyclic AMP. (NCI)" @default.
- NCIT_C21292 NCIT_NHC0 "C21292" @default.
- NCIT_C21292 NCIT_P106 "Gene or Genome" @default.
- NCIT_C21292 NCIT_P108 "Beta Adrenergic Receptor Gene" @default.
- NCIT_C21292 NCIT_P207 "C1332546" @default.
- NCIT_C21292 NCIT_P366 "Beta_Adrenergic_Receptor_Gene" @default.
- NCIT_C21292 NCIT_P96 "Beta Adrenergic Receptor" @default.
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- NCIT_C21292 normalizedInformationContent "84.132738204908478" @default.
- NCIT_C21292 referenceCount "11" @default.
- NCIT_C21292 hasExactSynonym "Beta Adrenergic Receptor Gene" @default.
- NCIT_C21292 type Class @default.
- NCIT_C21292 isDefinedBy ncit.owl @default.
- NCIT_C21292 label "Beta Adrenergic Receptor Gene" @default.
- NCIT_C21292 subClassOf NCIT_C16612 @default.
- NCIT_C21292 subClassOf NCIT_C20103 @default.
- NCIT_C21292 subClassOf NCIT_C20923 @default.
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- NCIT_C21292 subClassOf NCIT_C21295 @default.