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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C21490> ?p ?o ?g. }

• NCIT_C21490 IAO_0000115 "Ubiquitin carboxyl-terminal hydrolase BAP1 (729 aa, ~80 kDa) is encoded by the human BAP1 gene. This protein plays a role in both the negative regulation of cell proliferation and the deubiquitination of histones." @default.
• NCIT_C21490 NCIT_NHC0 "C21490" @default.
• NCIT_C21490 NCIT_P100 "603089" @default.
• NCIT_C21490 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
• NCIT_C21490 NCIT_P106 "Enzyme" @default.
• NCIT_C21490 NCIT_P107 "Ubiquitin Carboxyl-Terminal Hydrolase BAP1" @default.
• NCIT_C21490 NCIT_P108 "Ubiquitin Carboxyl-Terminal Hydrolase BAP1" @default.
• NCIT_C21490 NCIT_P207 "C1368335" @default.
• NCIT_C21490 NCIT_P322 "CTRP" @default.
• NCIT_C21490 NCIT_P366 "BRCA1_Associated_Protein-1" @default.
• NCIT_C21490 NCIT_P93 "Q92560" @default.
• NCIT_C21490 NCIT_P98 "Encoded by the ubiquitously expressed human BAP1 Gene. The 729-amino acid nuclear BRCA1 Associated Protein-1 contains an acidic region, a highly charged C- terminus, and putative nuclear localization signals. The N-terminus shows homology to ubiquitin C-terminal hydrolases, thiol proteases that catalyze ubiquitin proteolytic processing. BAP1 interacts with the BRCA1 RING finger, but this interaction is prevented by RING finger germline mutations of BRCA1 found in breast cancer kindreds. BAP1 enhances BRCA1-mediated inhibition of breast cancer cell growth, acting as a tumor suppressor in the BRCA1 growth control pathway. (from OMIM)" @default.
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• NCIT_C21490 NCIT_R54 NCIT_C26003 @default.
• NCIT_C21490 NCIT_R54 NCIT_C28404 @default.
• NCIT_C21490 normalizedInformationContent "100" @default.
• NCIT_C21490 referenceCount "1" @default.
• NCIT_C21490 hasExactSynonym "BAP1" @default.
• NCIT_C21490 hasExactSynonym "BRCA1 Associated Protein-1" @default.
• NCIT_C21490 hasExactSynonym "BRCA1-Associated Protein 1" @default.
• NCIT_C21490 hasExactSynonym "Cerebral Protein 6" @default.
• NCIT_C21490 hasExactSynonym "Cerebral Protein-13" @default.
• NCIT_C21490 hasExactSynonym "Cerebral Protein-6" @default.
• NCIT_C21490 hasExactSynonym "EC 3.4.19.12" @default.
• NCIT_C21490 hasExactSynonym "Ubiquitin Carboxyl-Terminal Hydrolase BAP1" @default.
• NCIT_C21490 inSubset NCIT_C116977 @default.
• NCIT_C21490 inSubset NCIT_C142799 @default.
• NCIT_C21490 inSubset NCIT_C142800 @default.
• NCIT_C21490 type Class @default.
• NCIT_C21490 isDefinedBy ncit.owl @default.
• NCIT_C21490 label "Ubiquitin Carboxyl-Terminal Hydrolase BAP1" @default.
• NCIT_C21490 subClassOf NCIT_C16481 @default.
• NCIT_C21490 subClassOf NCIT_C16554 @default.

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