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- NCIT_C215 IAO_0000115 "A racemic mixture of the r-isomer levalbuterol and s-albuterol, a short-acting sympathomimetic agent with bronchodilator activity. Albuterol stimulates beta-2 adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. Albuterol although to a lesser extent, also stimulates beta-1 adrenergic receptors, thereby increasing the force and rate of myocardial contraction." @default.
- NCIT_C215 NCIT_A5 NCIT_C47957 @default.
- NCIT_C215 NCIT_NHC0 "C215" @default.
- NCIT_C215 NCIT_P106 "Organic Chemical" @default.
- NCIT_C215 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C215 NCIT_P107 "Albuterol" @default.
- NCIT_C215 NCIT_P108 "Albuterol" @default.
- NCIT_C215 NCIT_P207 "C0001927" @default.
- NCIT_C215 NCIT_P210 "18559-94-9" @default.
- NCIT_C215 NCIT_P319 "QF8SVZ843E" @default.
- NCIT_C215 NCIT_P322 "CTRP" @default.
- NCIT_C215 NCIT_P322 "FDA" @default.
- NCIT_C215 NCIT_P350 "C13H21NO3" @default.
- NCIT_C215 NCIT_P366 "Albuterol" @default.
- NCIT_C215 NCIT_P368 "CHEBI:2549" @default.
- NCIT_C215 NCIT_P399 "81068" @default.
- NCIT_C215 normalizedInformationContent "100" @default.
- NCIT_C215 referenceCount "1" @default.
- NCIT_C215 hasExactSynonym "ALBUTEROL" @default.
- NCIT_C215 hasExactSynonym "Albuterol" @default.
- NCIT_C215 inSubset NCIT_C116977 @default.
- NCIT_C215 inSubset NCIT_C116978 @default.
- NCIT_C215 inSubset NCIT_C176424 @default.
- NCIT_C215 inSubset NCIT_C63923 @default.
- NCIT_C215 type Class @default.
- NCIT_C215 isDefinedBy ncit.owl @default.
- NCIT_C215 label "Albuterol" @default.
- NCIT_C215 subClassOf NCIT_C1908 @default.
- NCIT_C215 subClassOf NCIT_C1909 @default.
- NCIT_C215 subClassOf NCIT_C215 @default.
- NCIT_C215 subClassOf NCIT_C29712 @default.
- NCIT_C215 subClassOf NCIT_C29747 @default.
- NCIT_C215 subClassOf NCIT_C319 @default.
- NCIT_C215 subClassOf NCIT_C48149 @default.
- NCIT_C215 subClassOf NCIT_C78272 @default.
- NCIT_C215 subClassOf NCIT_C78273 @default.
- NCIT_C215 subClassOf NCIT_C87053 @default.