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- NCIT_C21730 NCIT_NHC0 "C21730" @default.
- NCIT_C21730 NCIT_P106 "Neoplastic Process" @default.
- NCIT_C21730 NCIT_P107 "High Grade Prostatic Intraepithelial Neoplasia" @default.
- NCIT_C21730 NCIT_P108 "High Grade Mouse Prostatic Intraepithelial Neoplasia" @default.
- NCIT_C21730 NCIT_P207 "C1522068" @default.
- NCIT_C21730 NCIT_P325 "High grade based on marked nuclear atypia, including macronucleoli, marked enlargement with hyperchromasia and irregular nuclear contours, abundant mitoses/apoptosis, luminal comedo necrosis." @default.
- NCIT_C21730 NCIT_P325 "In human, HGPIN occurs in previously normal prostate, so epithelial proliferation occurs within preexisting basement membrane bound glands and ducts. In transgenic mouse, creation of apparently increased glandular spaces compared to wild type mice is not necessarily indicative of invasive carcinoma. If such a lesion occurs uniformly throughout the prostate, for example, with lobular expansion by connecting large and small duct profiles (with similar cytologic atypia), and a symmetric lower power architecture, this should likely be considered an in situ process (e.g., images LPBTag12T5-7689DLP(10x); TRAMP538(10x); LPBTag12T7f-7874DLP(10x)). This concept is particularly evident when architecturally distinct foci of unequivocal stromal or periprostatic fat invasion (of small crowded glands, single cells, or nests of cells) occur against this more uniform symmetric lobular expansion HGPIN background." @default.
- NCIT_C21730 NCIT_P325 "Qualifier of local vs. extensive/diffuse can be added, similar to that described above for atypical hyperplasia. Focal as one to several foci, less than 50% of glands involved. Extensive/diffuse indicating involvement of greater than or equal to 50% of glands." @default.
- NCIT_C21730 NCIT_P325 "mPIN which has shown documented progression to invasive cancer." @default.
- NCIT_C21730 NCIT_P366 "High_Grade_Mouse_Prostatic_Intraepithelial_Neoplasia" @default.
- NCIT_C21730 NCIT_R24 NCIT_C156482 @default.
- NCIT_C21730 NCIT_R24 NCIT_C156660 @default.
- NCIT_C21730 NCIT_R24 NCIT_C26865 @default.
- NCIT_C21730 NCIT_R24 NCIT_C27019 @default.
- NCIT_C21730 NCIT_R24 NCIT_C27551 @default.
- NCIT_C21730 NCIT_R24 NCIT_C2991 @default.
- NCIT_C21730 NCIT_R24 NCIT_C3054 @default.
- NCIT_C21730 NCIT_R24 NCIT_C3262 @default.
- NCIT_C21730 NCIT_R24 NCIT_C3263 @default.
- NCIT_C21730 NCIT_R24 NCIT_C3341 @default.
- NCIT_C21730 NCIT_R24 NCIT_C3343 @default.
- NCIT_C21730 NCIT_R24 NCIT_C3430 @default.
- NCIT_C21730 NCIT_R24 NCIT_C3431 @default.
- NCIT_C21730 NCIT_R24 NCIT_C3674 @default.
- NCIT_C21730 NCIT_R24 NCIT_C3709 @default.
- NCIT_C21730 NCIT_R24 NCIT_C4741 @default.
- NCIT_C21730 NCIT_R24 NCIT_C4875 @default.
- NCIT_C21730 NCIT_R24 NCIT_C7057 @default.
- NCIT_C21730 NCIT_R24 NCIT_C8278 @default.
- NCIT_C21730 NCIT_R24 NCIT_C8366 @default.
- NCIT_C21730 NCIT_R25 NCIT_C22164 @default.
- NCIT_C21730 NCIT_R25 NCIT_C22165 @default.
- NCIT_C21730 NCIT_R25 NCIT_C22166 @default.
- NCIT_C21730 NCIT_R25 NCIT_C22188 @default.
- NCIT_C21730 NCIT_R25 NCIT_C24192 @default.
- NCIT_C21730 normalizedInformationContent "100" @default.
- NCIT_C21730 referenceCount "1" @default.
- NCIT_C21730 hasExactSynonym "High Grade Mouse Prostatic Intraepithelial Neoplasia" @default.
- NCIT_C21730 type Class @default.
- NCIT_C21730 isDefinedBy ncit.owl @default.
- NCIT_C21730 label "High Grade Mouse Prostatic Intraepithelial Neoplasia" @default.
- NCIT_C21730 subClassOf NCIT_C134533 @default.
- NCIT_C21730 subClassOf NCIT_C134576 @default.
- NCIT_C21730 subClassOf NCIT_C21614 @default.
- NCIT_C21730 subClassOf NCIT_C21637 @default.
- NCIT_C21730 subClassOf NCIT_C21722 @default.
- NCIT_C21730 subClassOf NCIT_C21723 @default.
- NCIT_C21730 subClassOf NCIT_C21728 @default.
- NCIT_C21730 subClassOf NCIT_C21730 @default.
- NCIT_C21730 subClassOf NCIT_C22187 @default.
- NCIT_C21730 subClassOf NCIT_C23987 @default.
- NCIT_C21730 subClassOf NCIT_C23988 @default.
- NCIT_C21730 subClassOf NCIT_C23990 @default.
- NCIT_C21730 subClassOf NCIT_C23992 @default.
- NCIT_C21730 subClassOf NCIT_C23993 @default.
- NCIT_C21730 subClassOf NCIT_C23995 @default.
- NCIT_C21730 subClassOf NCIT_C24030 @default.
- NCIT_C21730 subClassOf NCIT_C24031 @default.
- NCIT_C21730 subClassOf NCIT_C24032 @default.
- NCIT_C21730 subClassOf NCIT_C26390 @default.
- NCIT_C21730 subClassOf NCIT_C26396 @default.
- NCIT_C21730 subClassOf NCIT_C26399 @default.
- NCIT_C21730 subClassOf NCIT_C26400 @default.