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- NCIT_C2186 IAO_0000115 "A sulfonylurea compound containing aryl groups with potential antineoplastic activity. Originally developed as herbicides, diarylsulfonylureas have shown a broad spectrum of antitumor activity in vivo. The precise mechanism of antitumor action has not yet been elucidated, however, certain diarylsulfonylurea compounds have been shown in preliminary studies to exert antimitotic effects through their inhibition of tubulin polymerization, and others have been shown to be effective antitumor agents in animal models by the mechanism of uncoupling mitochondrial oxidative phosphorylation." @default.
- NCIT_C2186 NCIT_NHC0 "C2186" @default.
- NCIT_C2186 NCIT_P106 "Chemical Viewed Structurally" @default.
- NCIT_C2186 NCIT_P108 "Diarylsulfonylurea Compound" @default.
- NCIT_C2186 NCIT_P207 "C1511894" @default.
- NCIT_C2186 NCIT_P366 "Diarylsulfonylurea_Compound" @default.
- NCIT_C2186 normalizedInformationContent "92.730304365937428" @default.
- NCIT_C2186 referenceCount "3" @default.
- NCIT_C2186 hasExactSynonym "Diarylsulfonylurea Compound" @default.
- NCIT_C2186 hasExactSynonym "Diarylsulfonylureas" @default.
- NCIT_C2186 type Class @default.
- NCIT_C2186 isDefinedBy ncit.owl @default.
- NCIT_C2186 label "Diarylsulfonylurea Compound" @default.
- NCIT_C2186 subClassOf NCIT_C1908 @default.
- NCIT_C2186 subClassOf NCIT_C1909 @default.
- NCIT_C2186 subClassOf NCIT_C2186 @default.
- NCIT_C2186 subClassOf NCIT_C274 @default.