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- NCIT_C2209 IAO_0000115 "An immunoconjugate of the murine monoclonal antibody, 7E11-C5.3 (Capromab), conjugated to the linker-chelator, glycyl-tyrosyl-(N,-diethylenetriaminepentaacetic acid)-lysine hydrochloride (GYK-DTPA-HCl). Capromab, an IgG1 kappa immunoglobulin, binds specifically to a cytoplasmic epitope of prostate-specific membrane glycoprotein (PSMA) that is only expressed by prostatic epithelial cells (benign and malignant). Capromab pendetide can be used in diagnosis or detection of prostate cancer when labeled with Indium I-111, which emits gamma radiation and X-Ray photons that can be captured by gamma camera allowing imaging of PMSA expressing tissues." @default.
- NCIT_C2209 NCIT_NHC0 "C2209" @default.
- NCIT_C2209 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C2209 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C2209 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2209 NCIT_P108 "Capromab Pendetide" @default.
- NCIT_C2209 NCIT_P207 "C0529572" @default.
- NCIT_C2209 NCIT_P210 "145464-28-4" @default.
- NCIT_C2209 NCIT_P319 "BDO5072GRX" @default.
- NCIT_C2209 NCIT_P322 "FDA" @default.
- NCIT_C2209 NCIT_P325 "A substance used to detect prostate cancer. It contains a monoclonal antibody that binds to prostate cells, linked to a substance that can bind radioisotopes. Capromab pendetide is combined with indium 111 and injected into the body. A gamma camera (a special camera that detects radioactivity) is used to find prostate cancer cells in the body. Capromab pendetide is a type of immunoconjugate." @default.
- NCIT_C2209 NCIT_P350 "C32H48N7O14" @default.
- NCIT_C2209 NCIT_P366 "Capromab_Pendetide" @default.
- NCIT_C2209 normalizedInformationContent "100" @default.
- NCIT_C2209 referenceCount "1" @default.
- NCIT_C2209 hasExactSynonym "7E11-C5.3-GYK-DTPA" @default.
- NCIT_C2209 hasExactSynonym "CAPROMAB PENDETIDE" @default.
- NCIT_C2209 hasExactSynonym "CYT-356" @default.
- NCIT_C2209 hasExactSynonym "Capromab Pendetide" @default.
- NCIT_C2209 hasExactSynonym "Oncoscint Prostate" @default.
- NCIT_C2209 hasExactSynonym "ProstaScint" @default.
- NCIT_C2209 hasExactSynonym "Prostascint" @default.
- NCIT_C2209 hasExactSynonym "capromab pendetide" @default.
- NCIT_C2209 inSubset NCIT_C63923 @default.
- NCIT_C2209 type Class @default.
- NCIT_C2209 isDefinedBy ncit.owl @default.
- NCIT_C2209 label "Capromab Pendetide" @default.
- NCIT_C2209 subClassOf NCIT_C1512 @default.
- NCIT_C2209 subClassOf NCIT_C1908 @default.
- NCIT_C2209 subClassOf NCIT_C1909 @default.
- NCIT_C2209 subClassOf NCIT_C2209 @default.
- NCIT_C2209 subClassOf NCIT_C307 @default.
- NCIT_C2209 subClassOf NCIT_C308 @default.