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- NCIT_C2210 IAO_0000115 "An analog of thalidomide with potential antineoplastic activity that belongs to the functional class of agents called selective cytokine inhibitory drugs (SelCIDs). SelCIDs inhibit phosphodiesterase-4 (PDE 4), an enzyme involved in tumor necrosis factor alpha (TNF alpha) production. CC-1088 inhibits production of the cytokines vascular endothelial growth factor (VEGF) (a pro-angiogenic factor) and interleukin-6 (IL-6). (NCI04)" @default.
- NCIT_C2210 NCIT_A32 NCIT_C1909 @default.
- NCIT_C2210 NCIT_NHC0 "C2210" @default.
- NCIT_C2210 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2210 NCIT_P108 "Selective Cytokine Inhibitory Drug CC-1088" @default.
- NCIT_C2210 NCIT_P207 "C0879595" @default.
- NCIT_C2210 NCIT_P210 "192819-27-5" @default.
- NCIT_C2210 NCIT_P319 "95HB56U8P8" @default.
- NCIT_C2210 NCIT_P322 "FDA" @default.
- NCIT_C2210 NCIT_P322 "GDC" @default.
- NCIT_C2210 NCIT_P325 "A drug that is being studied in the treatment of cancer. It is similar but not identical to thalidomide. CC-1088 belongs to the family of drugs called angiogenesis inhibitors." @default.
- NCIT_C2210 NCIT_P329 "38051" @default.
- NCIT_C2210 NCIT_P330 "38051" @default.
- NCIT_C2210 NCIT_P366 "CC-1088" @default.
- NCIT_C2210 NCIT_P375 "Selective Cytokine Inhibitory Drug CC-1088" @default.
- NCIT_C2210 NCIT_P399 "38051" @default.
- NCIT_C2210 normalizedInformationContent "100" @default.
- NCIT_C2210 referenceCount "1" @default.
- NCIT_C2210 hasExactSynonym "CC-1088" @default.
- NCIT_C2210 hasExactSynonym "CDC-801" @default.
- NCIT_C2210 hasExactSynonym "Selective Cytokine Inhibitory Drug CC-1088" @default.
- NCIT_C2210 inSubset NCIT_C128784 @default.
- NCIT_C2210 inSubset NCIT_C157711 @default.
- NCIT_C2210 inSubset NCIT_C157712 @default.
- NCIT_C2210 inSubset NCIT_C176424 @default.
- NCIT_C2210 inSubset NCIT_C177537 @default.
- NCIT_C2210 inSubset NCIT_C63923 @default.
- NCIT_C2210 type Class @default.
- NCIT_C2210 isDefinedBy ncit.owl @default.
- NCIT_C2210 label "Selective Cytokine Inhibitory Drug CC-1088" @default.
- NCIT_C2210 subClassOf NCIT_C1908 @default.
- NCIT_C2210 subClassOf NCIT_C1909 @default.
- NCIT_C2210 subClassOf NCIT_C2210 @default.
- NCIT_C2210 subClassOf NCIT_C471 @default.
- NCIT_C2210 subClassOf NCIT_C744 @default.