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- NCIT_C224 IAO_0000115 "A structural isomer of hypoxanthine. Allopurinol inhibits xanthine oxidase, an enzyme that converts oxypurines to uric acid. By blocking the production of uric acid, this agent decreases serum and urine concentrations of uric acid, thereby providing protection against uric acid-mediated end organ damage in conditions associated with excessive production of uric acid, i.e. the massive cell lysis associated with the treatment of some malignancies. (NCI04)" @default.
- NCIT_C224 NCIT_A5 NCIT_C2564 @default.
- NCIT_C224 NCIT_A7 NCIT_C39587 @default.
- NCIT_C224 NCIT_NHC0 "C224" @default.
- NCIT_C224 NCIT_P106 "Organic Chemical" @default.
- NCIT_C224 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C224 NCIT_P107 "Allopurinol" @default.
- NCIT_C224 NCIT_P108 "Allopurinol" @default.
- NCIT_C224 NCIT_P175 "101655" @default.
- NCIT_C224 NCIT_P175 "1390" @default.
- NCIT_C224 NCIT_P207 "C0002144" @default.
- NCIT_C224 NCIT_P210 "315-30-0" @default.
- NCIT_C224 NCIT_P319 "63CZ7GJN5I" @default.
- NCIT_C224 NCIT_P322 "CTRP" @default.
- NCIT_C224 NCIT_P322 "FDA" @default.
- NCIT_C224 NCIT_P325 "A drug that lowers high levels of uric acid (a byproduct of metabolism) in the blood caused by some cancer treatments." @default.
- NCIT_C224 NCIT_P329 "38452" @default.
- NCIT_C224 NCIT_P330 "38452" @default.
- NCIT_C224 NCIT_P350 "C5H4N4O" @default.
- NCIT_C224 NCIT_P366 "Allopurinol" @default.
- NCIT_C224 NCIT_P368 "CHEBI:40279" @default.
- NCIT_C224 NCIT_P399 "38452" @default.
- NCIT_C224 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C224 referenceCount "2" @default.
- NCIT_C224 hasExactSynonym "1,5-Dihydro-4H-pyrazolo[3,4-d]pryimidin-4-one" @default.
- NCIT_C224 hasExactSynonym "1,5-Dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one" @default.
- NCIT_C224 hasExactSynonym "1H-Pyrazolo[3,4-d]pyrimidin-4-ol" @default.
- NCIT_C224 hasExactSynonym "4'-HPP" @default.
- NCIT_C224 hasExactSynonym "4-Hydroxypyrazolo[3,4-d]pyrimidine" @default.
- NCIT_C224 hasExactSynonym "ALLOPURINOL" @default.
- NCIT_C224 hasExactSynonym "Allopurinol" @default.
- NCIT_C224 hasExactSynonym "Lopurin" @default.
- NCIT_C224 hasExactSynonym "Sigapurol" @default.
- NCIT_C224 hasExactSynonym "Zurinol" @default.
- NCIT_C224 hasExactSynonym "allopurinol" @default.
- NCIT_C224 inSubset NCIT_C116977 @default.
- NCIT_C224 inSubset NCIT_C116978 @default.
- NCIT_C224 inSubset NCIT_C176424 @default.
- NCIT_C224 inSubset NCIT_C63923 @default.
- NCIT_C224 type Class @default.
- NCIT_C224 isDefinedBy ncit.owl @default.
- NCIT_C224 label "Allopurinol" @default.
- NCIT_C224 subClassOf NCIT_C1637 @default.
- NCIT_C224 subClassOf NCIT_C1908 @default.
- NCIT_C224 subClassOf NCIT_C1909 @default.
- NCIT_C224 subClassOf NCIT_C224 @default.
- NCIT_C224 subClassOf NCIT_C26170 @default.
- NCIT_C224 subClassOf NCIT_C471 @default.
- NCIT_C224 subClassOf NCIT_C921 @default.