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- NCIT_C2241 IAO_0000115 "A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 (IL-2) with potential immunostimulating and antineoplastic activities. Originally developed for the eradication of smallpox, MVA is a highly attenuated and replication-defective strain incapable of virion assembly and exerts potent immunostimulatory activity against antigens. Vaccination with mesmulogene ancovacivec may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) responses against tumor cells expressing MUC1, a tumor associated antigen, resulting in tumor cell lysis. Expression of IL-2 augments the specific CTL response against MUC1 expressing cells." @default.
- NCIT_C2241 NCIT_NHC0 "C2241" @default.
- NCIT_C2241 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C2241 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2241 NCIT_P107 "Mesmulogene Ancovacivec" @default.
- NCIT_C2241 NCIT_P108 "Mesmulogene Ancovacivec" @default.
- NCIT_C2241 NCIT_P207 "C0879624" @default.
- NCIT_C2241 NCIT_P210 "1246525-59-6" @default.
- NCIT_C2241 NCIT_P319 "WQQ9XZH2CC" @default.
- NCIT_C2241 NCIT_P322 "CTRP" @default.
- NCIT_C2241 NCIT_P322 "FDA" @default.
- NCIT_C2241 NCIT_P325 "A substance that is being studied as an anticancer drug." @default.
- NCIT_C2241 NCIT_P329 "37853" @default.
- NCIT_C2241 NCIT_P330 "37853" @default.
- NCIT_C2241 NCIT_P366 "TG4010" @default.
- NCIT_C2241 NCIT_P399 "37853" @default.
- NCIT_C2241 normalizedInformationContent "100" @default.
- NCIT_C2241 referenceCount "1" @default.
- NCIT_C2241 hasExactSynonym "MESMULOGENE ANCOVACIVEC" @default.
- NCIT_C2241 hasExactSynonym "MVA-MUC1-IL2 Vaccine" @default.
- NCIT_C2241 hasExactSynonym "MVA-MUC1-IL2" @default.
- NCIT_C2241 hasExactSynonym "Mesmulogene Ancovacivec" @default.
- NCIT_C2241 hasExactSynonym "Modified Vaccinia Ankara Encoding Human MUC-1 Antigen and Interleukin-2 Suspension" @default.
- NCIT_C2241 hasExactSynonym "TG4010" @default.
- NCIT_C2241 inSubset NCIT_C116977 @default.
- NCIT_C2241 inSubset NCIT_C116978 @default.
- NCIT_C2241 inSubset NCIT_C128784 @default.
- NCIT_C2241 inSubset NCIT_C176424 @default.
- NCIT_C2241 inSubset NCIT_C63923 @default.
- NCIT_C2241 type Class @default.
- NCIT_C2241 isDefinedBy ncit.owl @default.
- NCIT_C2241 label "Mesmulogene Ancovacivec" @default.
- NCIT_C2241 subClassOf NCIT_C1572 @default.
- NCIT_C2241 subClassOf NCIT_C1908 @default.
- NCIT_C2241 subClassOf NCIT_C1909 @default.
- NCIT_C2241 subClassOf NCIT_C1962 @default.
- NCIT_C2241 subClassOf NCIT_C2241 @default.
- NCIT_C2241 subClassOf NCIT_C2313 @default.
- NCIT_C2241 subClassOf NCIT_C307 @default.
- NCIT_C2241 subClassOf NCIT_C308 @default.
- NCIT_C2241 subClassOf NCIT_C923 @default.
- NCIT_C2241 subClassOf NCIT_C96404 @default.