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- NCIT_C2319 IAO_0000115 "Any substance that inhibits steroid 5-alpha-reductase, an enzyme that converts testosterone into dihydrotestosterone (DHT). Since DHT has three times greater affinity for androgen receptors than testosterone, inhibition of 5-alpha-reductase results in a strong reduction in the androgenic effects of testosterone." @default.
- NCIT_C2319 NCIT_NHC0 "C2319" @default.
- NCIT_C2319 NCIT_P106 "Chemical Viewed Functionally" @default.
- NCIT_C2319 NCIT_P108 "5 Alpha-Reductase Inhibitor" @default.
- NCIT_C2319 NCIT_P207 "C1318898" @default.
- NCIT_C2319 NCIT_P325 "A substance that blocks an enzyme needed by the body to make dihydrotestosterone (a male sex hormone made from testosterone). Dihydrotestosterone can cause the prostate to grow. 5-alpha reductase inhibitors are used to shrink an enlarged prostate gland and to improve the flow of urine in a condition called benign prostatic hyperplasia (BPH). A 5-alpha reductase inhibitor is a type of enzyme inhibitor." @default.
- NCIT_C2319 NCIT_P366 "_5_Alpha-Reductase_Inhibitor" @default.
- NCIT_C2319 NCIT_P368 "CHEBI:50781" @default.
- NCIT_C2319 normalizedInformationContent "86.239998175184226" @default.
- NCIT_C2319 referenceCount "8" @default.
- NCIT_C2319 hasExactSynonym "5 Alpha-Reductase Inhibitor" @default.
- NCIT_C2319 hasExactSynonym "5-alpha reductase inhibitor" @default.
- NCIT_C2319 hasExactSynonym "Steroid 5-alpha-reductase Inhibitor" @default.
- NCIT_C2319 type Class @default.
- NCIT_C2319 isDefinedBy ncit.owl @default.
- NCIT_C2319 label "5 Alpha-Reductase Inhibitor" @default.
- NCIT_C2319 subClassOf NCIT_C147908 @default.
- NCIT_C2319 subClassOf NCIT_C1892 @default.
- NCIT_C2319 subClassOf NCIT_C1908 @default.
- NCIT_C2319 subClassOf NCIT_C1909 @default.
- NCIT_C2319 subClassOf NCIT_C2319 @default.
- NCIT_C2319 subClassOf NCIT_C242 @default.
- NCIT_C2319 subClassOf NCIT_C471 @default.
- NCIT_C2319 subClassOf NCIT_C547 @default.