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- NCIT_C235 IAO_0000115 "A synthetic derivative of pterins with antineoplastic and immunosuppressive properties. As a folate analogue, aminopterin competes for the folate binding site of the enzyme dihydrofolate reductase, thereby blocking tetrahydrofolate synthesis, and resulting in depletion of nucleotide precursors and inhibition of DNA, RNA and protein synthesis. (NCI04)" @default.
- NCIT_C235 NCIT_A32 NCIT_C1909 @default.
- NCIT_C235 NCIT_A5 NCIT_C74554 @default.
- NCIT_C235 NCIT_NHC0 "C235" @default.
- NCIT_C235 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C235 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C235 NCIT_P108 "Aminopterin" @default.
- NCIT_C235 NCIT_P175 "739" @default.
- NCIT_C235 NCIT_P207 "C0002583" @default.
- NCIT_C235 NCIT_P210 "54-62-6" @default.
- NCIT_C235 NCIT_P319 "JYB41CTM2Q" @default.
- NCIT_C235 NCIT_P322 "FDA" @default.
- NCIT_C235 NCIT_P322 "GDC" @default.
- NCIT_C235 NCIT_P325 "An anticancer drug that belongs to the family of drugs called antimetabolites." @default.
- NCIT_C235 NCIT_P329 "39141" @default.
- NCIT_C235 NCIT_P330 "39141" @default.
- NCIT_C235 NCIT_P350 "C19H20N8O5" @default.
- NCIT_C235 NCIT_P366 "Aminopterin" @default.
- NCIT_C235 NCIT_P368 "CHEBI:22526" @default.
- NCIT_C235 NCIT_P375 "Aminopterin" @default.
- NCIT_C235 NCIT_P399 "39141" @default.
- NCIT_C235 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C235 referenceCount "2" @default.
- NCIT_C235 hasExactSynonym "4-Amino-PGA" @default.
- NCIT_C235 hasExactSynonym "4-Aminofolic Acid" @default.
- NCIT_C235 hasExactSynonym "4-Aminofolic acid" @default.
- NCIT_C235 hasExactSynonym "4-Aminopteroyl-glutamic Acid" @default.
- NCIT_C235 hasExactSynonym "4-Aminopteroylglutamic Acid" @default.
- NCIT_C235 hasExactSynonym "4-Aminopteroylglutamic acid" @default.
- NCIT_C235 hasExactSynonym "AMINOPTERIN" @default.
- NCIT_C235 hasExactSynonym "APGA" @default.
- NCIT_C235 hasExactSynonym "Aminopterin" @default.
- NCIT_C235 hasExactSynonym "Aminopteroylglutamic Acid" @default.
- NCIT_C235 hasExactSynonym "aminopterin" @default.
- NCIT_C235 inSubset NCIT_C128784 @default.
- NCIT_C235 inSubset NCIT_C157711 @default.
- NCIT_C235 inSubset NCIT_C157712 @default.
- NCIT_C235 inSubset NCIT_C176424 @default.
- NCIT_C235 inSubset NCIT_C177537 @default.
- NCIT_C235 inSubset NCIT_C63923 @default.
- NCIT_C235 type Class @default.
- NCIT_C235 isDefinedBy ncit.owl @default.
- NCIT_C235 label "Aminopterin" @default.
- NCIT_C235 subClassOf NCIT_C186664 @default.
- NCIT_C235 subClassOf NCIT_C1908 @default.
- NCIT_C235 subClassOf NCIT_C1909 @default.
- NCIT_C235 subClassOf NCIT_C2153 @default.
- NCIT_C235 subClassOf NCIT_C235 @default.
- NCIT_C235 subClassOf NCIT_C272 @default.
- NCIT_C235 subClassOf NCIT_C274 @default.
- NCIT_C235 subClassOf NCIT_C471 @default.
- NCIT_C235 subClassOf NCIT_C511 @default.