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- NCIT_C2366 IAO_0000115 "An antifolate derived from diaminopyrimidine with cytotoxic properties. With a mechanism of action similar to that of methotrexate (MTX), m-azidopyrimethamine blocks tetrahydrofolate synthesis, resulting in depletion of nucleotide precursors and inhibition of DNA, RNA and protein synthesis. This agent is more lipophilic but less potent than MTX. (NCI04)" @default.
- NCIT_C2366 NCIT_NHC0 "C2366" @default.
- NCIT_C2366 NCIT_P106 "Organic Chemical" @default.
- NCIT_C2366 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2366 NCIT_P108 "M-Azidopyrimethamine" @default.
- NCIT_C2366 NCIT_P175 "382050" @default.
- NCIT_C2366 NCIT_P207 "C0280485" @default.
- NCIT_C2366 NCIT_P329 "40860" @default.
- NCIT_C2366 NCIT_P330 "40860" @default.
- NCIT_C2366 NCIT_P366 "M-Azidopyrimethamine" @default.
- NCIT_C2366 NCIT_P399 "40860" @default.
- NCIT_C2366 normalizedInformationContent "100" @default.
- NCIT_C2366 referenceCount "1" @default.
- NCIT_C2366 hasExactSynonym "M-Azidopyrimethamine" @default.
- NCIT_C2366 hasExactSynonym "MZP" @default.
- NCIT_C2366 inSubset NCIT_C176424 @default.
- NCIT_C2366 type Class @default.
- NCIT_C2366 isDefinedBy ncit.owl @default.
- NCIT_C2366 label "M-Azidopyrimethamine" @default.
- NCIT_C2366 subClassOf NCIT_C186664 @default.
- NCIT_C2366 subClassOf NCIT_C1908 @default.
- NCIT_C2366 subClassOf NCIT_C1909 @default.
- NCIT_C2366 subClassOf NCIT_C2366 @default.
- NCIT_C2366 subClassOf NCIT_C272 @default.
- NCIT_C2366 subClassOf NCIT_C274 @default.
- NCIT_C2366 subClassOf NCIT_C511 @default.