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- NCIT_C238 IAO_0000115 "A polyene antifungal antibiotic produced by Streptomyces nodosus, with antifungal activity. Amphotericin B binds to ergosterol, an essential component of the fungal cell membrane, thereby causing depolarization of the membrane and altering cell membrane permeability. This leads to leakage of important intracellular components, cell rupture, and eventually cell death. This agent may also induce oxidative damage in fungal cells and has been reported to stimulate host immune cells." @default.
- NCIT_C238 NCIT_A5 NCIT_C62201 @default.
- NCIT_C238 NCIT_NHC0 "C238" @default.
- NCIT_C238 NCIT_P106 "Antibiotic" @default.
- NCIT_C238 NCIT_P106 "Organic Chemical" @default.
- NCIT_C238 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C238 NCIT_P108 "Amphotericin B" @default.
- NCIT_C238 NCIT_P175 "527017" @default.
- NCIT_C238 NCIT_P207 "C0002679" @default.
- NCIT_C238 NCIT_P210 "1397-89-3" @default.
- NCIT_C238 NCIT_P319 "7XU7A7DROE" @default.
- NCIT_C238 NCIT_P322 "FDA" @default.
- NCIT_C238 NCIT_P325 "A drug used in the treatment of infections caused by fungi. It is a type of antifungal." @default.
- NCIT_C238 NCIT_P350 "C47H73NO17" @default.
- NCIT_C238 NCIT_P366 "Amphotercin_B" @default.
- NCIT_C238 NCIT_P368 "CHEBI:2682" @default.
- NCIT_C238 normalizedInformationContent "92.730304365937428" @default.
- NCIT_C238 referenceCount "3" @default.
- NCIT_C238 hasExactSynonym "AMPHOTERICIN B" @default.
- NCIT_C238 hasExactSynonym "AmB" @default.
- NCIT_C238 hasExactSynonym "Amphocil" @default.
- NCIT_C238 hasExactSynonym "Amphotec" @default.
- NCIT_C238 hasExactSynonym "Amphotericin B" @default.
- NCIT_C238 hasExactSynonym "Amphotericin b" @default.
- NCIT_C238 hasExactSynonym "amphotericin B" @default.
- NCIT_C238 inSubset NCIT_C63923 @default.
- NCIT_C238 type Class @default.
- NCIT_C238 isDefinedBy ncit.owl @default.
- NCIT_C238 label "Amphotericin B" @default.
- NCIT_C238 subClassOf NCIT_C1908 @default.
- NCIT_C238 subClassOf NCIT_C1909 @default.
- NCIT_C238 subClassOf NCIT_C238 @default.
- NCIT_C238 subClassOf NCIT_C254 @default.
- NCIT_C238 subClassOf NCIT_C514 @default.