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- NCIT_C2429 IAO_0000115 "An autologous sarcoma cell vaccine with potential immunostimulatory activity. Tumor cells harvested from a patient with sarcoma are transfected with a plasmid DNA encoding for human sargramostim (GM-CSF) using a particle-mediated gene transfer (PMGT) technique, which avoids the use of infectious components. Vaccination with an autologous sargramostim sarcoma vaccine produces high levels of GM-CSF, a cytokine that enhances antigen presentation by activated macrophages and increases the recognition of weakly immunogenic tumors by cytotoxic T-lymphocytes." @default.
- NCIT_C2429 NCIT_NHC0 "C2429" @default.
- NCIT_C2429 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C2429 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2429 NCIT_P108 "Sargramostim Plasmid DNA Sarcoma Vaccine" @default.
- NCIT_C2429 NCIT_P207 "C0393070" @default.
- NCIT_C2429 NCIT_P329 "42678" @default.
- NCIT_C2429 NCIT_P330 "42678" @default.
- NCIT_C2429 NCIT_P366 "Sargramostim_Plasmid_DNA_Sarcoma_Vaccine" @default.
- NCIT_C2429 NCIT_P399 "42678" @default.
- NCIT_C2429 normalizedInformationContent "100" @default.
- NCIT_C2429 referenceCount "1" @default.
- NCIT_C2429 hasExactSynonym "GM-CSF plasmid DNA sarcoma vaccine" @default.
- NCIT_C2429 hasExactSynonym "Sargramostim Plasmid DNA Sarcoma Vaccine" @default.
- NCIT_C2429 inSubset NCIT_C128784 @default.
- NCIT_C2429 inSubset NCIT_C176424 @default.
- NCIT_C2429 type Class @default.
- NCIT_C2429 isDefinedBy ncit.owl @default.
- NCIT_C2429 label "Sargramostim Plasmid DNA Sarcoma Vaccine" @default.
- NCIT_C2429 subClassOf NCIT_C129820 @default.
- NCIT_C2429 subClassOf NCIT_C1663 @default.
- NCIT_C2429 subClassOf NCIT_C1908 @default.
- NCIT_C2429 subClassOf NCIT_C1909 @default.
- NCIT_C2429 subClassOf NCIT_C2429 @default.
- NCIT_C2429 subClassOf NCIT_C274 @default.
- NCIT_C2429 subClassOf NCIT_C307 @default.
- NCIT_C2429 subClassOf NCIT_C308 @default.
- NCIT_C2429 subClassOf NCIT_C39619 @default.
- NCIT_C2429 subClassOf NCIT_C923 @default.