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- NCIT_C2445 IAO_0000115 "A whole cell vaccine comprised of irradiated allogenic pancreatic tumor cells transfected with a plasmid DNA encoding human sargramostim (GM-CSF). Vaccination results in expression of GM-CSF, which induces proliferation and differentiation of hematopoietic lineage cells as well as stimulating macrophage and dendritic cell functions in antigen presentation and antitumor cell-mediated immunity. Furthermore, administration of this pancreatic tumor cell vaccine may elicit a cytotoxic T lymphocyte (CTL) response against similar host tumor cells, resulting in decreased tumor growth." @default.
- NCIT_C2445 NCIT_NHC0 "C2445" @default.
- NCIT_C2445 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C2445 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2445 NCIT_P107 "Sargramostim Plasmid DNA Pancreatic Tumor Cell Vaccine" @default.
- NCIT_C2445 NCIT_P108 "Sargramostim Plasmid DNA Pancreatic Tumor Cell Vaccine" @default.
- NCIT_C2445 NCIT_P207 "C0677758" @default.
- NCIT_C2445 NCIT_P322 "CTRP" @default.
- NCIT_C2445 NCIT_P329 "42810" @default.
- NCIT_C2445 NCIT_P330 "42810" @default.
- NCIT_C2445 NCIT_P366 "Sargramostim_Plasmid_DNA_Pancreatic_Tumor_Cell_Vaccine" @default.
- NCIT_C2445 NCIT_P399 "42810" @default.
- NCIT_C2445 normalizedInformationContent "100" @default.
- NCIT_C2445 referenceCount "1" @default.
- NCIT_C2445 hasExactSynonym "GM-CSF plasmid DNA pancreatic tumor cell vaccine" @default.
- NCIT_C2445 hasExactSynonym "Sargramostim Plasmid DNA Pancreatic Tumor Cell Vaccine" @default.
- NCIT_C2445 inSubset NCIT_C116977 @default.
- NCIT_C2445 inSubset NCIT_C116978 @default.
- NCIT_C2445 inSubset NCIT_C128784 @default.
- NCIT_C2445 inSubset NCIT_C176424 @default.
- NCIT_C2445 type Class @default.
- NCIT_C2445 isDefinedBy ncit.owl @default.
- NCIT_C2445 label "Sargramostim Plasmid DNA Pancreatic Tumor Cell Vaccine" @default.
- NCIT_C2445 subClassOf NCIT_C129820 @default.
- NCIT_C2445 subClassOf NCIT_C1663 @default.
- NCIT_C2445 subClassOf NCIT_C1908 @default.
- NCIT_C2445 subClassOf NCIT_C1909 @default.
- NCIT_C2445 subClassOf NCIT_C1983 @default.
- NCIT_C2445 subClassOf NCIT_C2341 @default.
- NCIT_C2445 subClassOf NCIT_C2445 @default.
- NCIT_C2445 subClassOf NCIT_C274 @default.
- NCIT_C2445 subClassOf NCIT_C307 @default.
- NCIT_C2445 subClassOf NCIT_C308 @default.
- NCIT_C2445 subClassOf NCIT_C923 @default.