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- NCIT_C2455 IAO_0000115 "A recombinant form of the endogenous human keratinocyte growth factor with cell growth promoting activity. Palifermin acts in the manner similar to the endogenous keratinocyte growth factor that binds to keratinocyte growth factor receptors on the epithelial cell surface in the lining of mouth and gastrointestinal tract. This results in stimulation of epithelial cell proliferation, differentiation and upregulation of cytoprotective mechanisms." @default.
- NCIT_C2455 NCIT_NHC0 "C2455" @default.
- NCIT_C2455 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C2455 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2455 NCIT_P107 "Palifermin" @default.
- NCIT_C2455 NCIT_P108 "Palifermin" @default.
- NCIT_C2455 NCIT_P207 "C0677829" @default.
- NCIT_C2455 NCIT_P210 "162394-19-6" @default.
- NCIT_C2455 NCIT_P302 "Severe oral mucositis with hematologic malignancies, chemotherapy- and radiotherapy-induced" @default.
- NCIT_C2455 NCIT_P319 "QMS40680K6" @default.
- NCIT_C2455 NCIT_P322 "CTRP" @default.
- NCIT_C2455 NCIT_P322 "FDA" @default.
- NCIT_C2455 NCIT_P325 "A form of keratinocyte growth factor (KGF) that is made in the laboratory. KGF stimulates the growth of cells that line the surface of the mouth and intestinal tract. Kepivance is used to prevent and treat oral mucositis (mouth sores) caused by high-dose chemotherapy and radiation therapy in leukemia and lymphoma. It is also being studied in the prevention and treatment of oral mucositis and dysphagia (difficulty swallowing) in other types of cancer. Kepivance is a type of recombinant human keratinocyte growth factor." @default.
- NCIT_C2455 NCIT_P329 "42905" @default.
- NCIT_C2455 NCIT_P330 "42905" @default.
- NCIT_C2455 NCIT_P366 "Recombinant_Human_Keratinocyte_Growth_Factor" @default.
- NCIT_C2455 NCIT_P399 "42905" @default.
- NCIT_C2455 normalizedInformationContent "100" @default.
- NCIT_C2455 referenceCount "1" @default.
- NCIT_C2455 hasExactSynonym "Growth Factor, Recombinant Human Keratinocyte" @default.
- NCIT_C2455 hasExactSynonym "Kepivance" @default.
- NCIT_C2455 hasExactSynonym "Keratinocyte Growth Factor, Recombinant Human" @default.
- NCIT_C2455 hasExactSynonym "PALIFERMIN" @default.
- NCIT_C2455 hasExactSynonym "Palifermin" @default.
- NCIT_C2455 hasExactSynonym "Recombinant Human Keratinocyte Growth Factor" @default.
- NCIT_C2455 hasExactSynonym "palifermin" @default.
- NCIT_C2455 hasExactSynonym "rhKGF" @default.
- NCIT_C2455 hasExactSynonym "rhu Keratinocyte Growth Factor" @default.
- NCIT_C2455 inSubset NCIT_C116977 @default.
- NCIT_C2455 inSubset NCIT_C116978 @default.
- NCIT_C2455 inSubset NCIT_C176424 @default.
- NCIT_C2455 inSubset NCIT_C63923 @default.
- NCIT_C2455 type Class @default.
- NCIT_C2455 isDefinedBy ncit.owl @default.
- NCIT_C2455 label "Palifermin" @default.
- NCIT_C2455 subClassOf NCIT_C1908 @default.
- NCIT_C2455 subClassOf NCIT_C1909 @default.
- NCIT_C2455 subClassOf NCIT_C2455 @default.
- NCIT_C2455 subClassOf NCIT_C307 @default.
- NCIT_C2455 subClassOf NCIT_C496 @default.
- NCIT_C2455 subClassOf NCIT_C530 @default.