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- NCIT_C2500 IAO_0000115 "A peptide, amino acid derivative, and/or organic acid extracted from blood serum, urine, or synthesized chemically, that inhibits the methylation of nucleic acids and the incorporation of L-glutamine into tumor-cell proteins. These agents also intercalate into DNA, leading to cell cycle arrest in the G1 phase and inhibition of mitosis and terminal cell differentiation. In addition, antineoplastons may inhibit RAS oncogene expression and activate the tumor suppressor gene p53, resulting in cell differentiation and apoptosis. (NCI04)" @default.
- NCIT_C2500 NCIT_NHC0 "C2500" @default.
- NCIT_C2500 NCIT_P106 "Chemical Viewed Functionally" @default.
- NCIT_C2500 NCIT_P108 "Antineoplaston Agent" @default.
- NCIT_C2500 NCIT_P207 "C1516025" @default.
- NCIT_C2500 NCIT_P325 "A substance isolated from normal human blood and urine that is being tested as a type of treatment for some tumors and AIDS." @default.
- NCIT_C2500 NCIT_P366 "Antineoplaston_Agent" @default.
- NCIT_C2500 normalizedInformationContent "89.350088392419622" @default.
- NCIT_C2500 referenceCount "5" @default.
- NCIT_C2500 hasExactSynonym "Antineoplaston Agent" @default.
- NCIT_C2500 hasExactSynonym "Antineoplastons" @default.
- NCIT_C2500 hasExactSynonym "antineoplaston" @default.
- NCIT_C2500 type Class @default.
- NCIT_C2500 isDefinedBy ncit.owl @default.
- NCIT_C2500 label "Antineoplaston Agent" @default.
- NCIT_C2500 subClassOf NCIT_C1908 @default.
- NCIT_C2500 subClassOf NCIT_C1909 @default.
- NCIT_C2500 subClassOf NCIT_C1934 @default.
- NCIT_C2500 subClassOf NCIT_C2122 @default.
- NCIT_C2500 subClassOf NCIT_C2500 @default.
- NCIT_C2500 subClassOf NCIT_C274 @default.