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- NCIT_C2516 IAO_0000115 "An antineoplastic antibiotic that is structurally similar to the benzoquinone ansamycin antibiotic geldanamycin. A geldanamycin analogue binds to HSP90, a chaperone protein that aids in the assembly, maturation, and folding of proteins. Subsequently, the function of HSP90 is inhibited, leading to the degradation and depletion of client proteins such as kinases and transcription factors involved with cell cycle regulation and signal transduction." @default.
- NCIT_C2516 NCIT_NHC0 "C2516" @default.
- NCIT_C2516 NCIT_P106 "Antibiotic" @default.
- NCIT_C2516 NCIT_P106 "Organic Chemical" @default.
- NCIT_C2516 NCIT_P108 "Geldanamycin Analogue" @default.
- NCIT_C2516 NCIT_P175 "210757" @default.
- NCIT_C2516 NCIT_P175 "255104" @default.
- NCIT_C2516 NCIT_P175 "255107" @default.
- NCIT_C2516 NCIT_P207 "C0796552" @default.
- NCIT_C2516 NCIT_P325 "An antineoplastic antibiotic drug that belongs to the family of drugs called ansamycins." @default.
- NCIT_C2516 NCIT_P366 "Geldanamycin_Analogue" @default.
- NCIT_C2516 NCIT_R124 NCIT_C17710 @default.
- NCIT_C2516 NCIT_R124 NCIT_C17828 @default.
- NCIT_C2516 NCIT_R124 NCIT_C18219 @default.
- NCIT_C2516 NCIT_R124 NCIT_C19986 @default.
- NCIT_C2516 NCIT_R124 NCIT_C40952 @default.
- NCIT_C2516 NCIT_R124 NCIT_C41571 @default.
- NCIT_C2516 NCIT_R125 NCIT_C17133 @default.
- NCIT_C2516 NCIT_R125 NCIT_C17710 @default.
- NCIT_C2516 NCIT_R125 NCIT_C17828 @default.
- NCIT_C2516 NCIT_R125 NCIT_C18104 @default.
- NCIT_C2516 NCIT_R125 NCIT_C19406 @default.
- NCIT_C2516 NCIT_R125 NCIT_C19536 @default.
- NCIT_C2516 NCIT_R125 NCIT_C19903 @default.
- NCIT_C2516 NCIT_R125 NCIT_C19986 @default.
- NCIT_C2516 NCIT_R125 NCIT_C20480 @default.
- NCIT_C2516 NCIT_R125 NCIT_C21198 @default.
- NCIT_C2516 NCIT_R125 NCIT_C28498 @default.
- NCIT_C2516 NCIT_R125 NCIT_C40673 @default.
- NCIT_C2516 NCIT_R125 NCIT_C40821 @default.
- NCIT_C2516 NCIT_R125 NCIT_C61559 @default.
- NCIT_C2516 NCIT_R146 NCIT_C16672 @default.
- NCIT_C2516 NCIT_R146 NCIT_C17021 @default.
- NCIT_C2516 NCIT_R146 NCIT_C17766 @default.
- NCIT_C2516 NCIT_R146 NCIT_C20130 @default.
- NCIT_C2516 NCIT_R146 NCIT_C26548 @default.
- NCIT_C2516 normalizedInformationContent "84.76342111748103" @default.
- NCIT_C2516 referenceCount "10" @default.
- NCIT_C2516 hasExactSynonym "Geldanamycin Analog" @default.
- NCIT_C2516 hasExactSynonym "Geldanamycin Analogue" @default.
- NCIT_C2516 hasExactSynonym "geldanamycin analog" @default.
- NCIT_C2516 type Class @default.
- NCIT_C2516 isDefinedBy ncit.owl @default.
- NCIT_C2516 label "Geldanamycin Analogue" @default.
- NCIT_C2516 subClassOf B0182d92798733428a6adcb504b12d68d @default.
- NCIT_C2516 subClassOf B0e63c5cf37cef858f22ca0f0e12da071 @default.
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- NCIT_C2516 subClassOf NCIT_C1003 @default.
- NCIT_C2516 subClassOf NCIT_C129824 @default.
- NCIT_C2516 subClassOf NCIT_C186664 @default.
- NCIT_C2516 subClassOf NCIT_C1908 @default.
- NCIT_C2516 subClassOf NCIT_C1909 @default.
- NCIT_C2516 subClassOf NCIT_C2189 @default.
- NCIT_C2516 subClassOf NCIT_C2516 @default.
- NCIT_C2516 subClassOf NCIT_C259 @default.
- NCIT_C2516 subClassOf NCIT_C274 @default.
- NCIT_C2516 subClassOf NCIT_C74526 @default.