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- NCIT_C2541 IAO_0000115 "A radioimmunoconjugate consisting of HMFG1, a humanized monoclonal antibody directed against the tumor associated antigen mucin-1 (MUC-1), labeled with the beta-emitting radioisotope yttrium 90 (Y-90), with potential antineoplastic activities. Upon administration, the monoclonal antibody moiety targets and binds to MUC-1 on the surface of certain tumor cells. Upon binding and internalization, pemtumomab and delivers a cytotoxic dose of beta radiation to MUC1-expressing tumor cells. MUC1, a glycoprotein overexpressed on the surface of a variety of cancer cells, plays a key role in tumor cell survival and proliferation." @default.
- NCIT_C2541 NCIT_A32 NCIT_C1909 @default.
- NCIT_C2541 NCIT_NHC0 "C2541" @default.
- NCIT_C2541 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C2541 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2541 NCIT_P108 "Y 90 Monoclonal Antibody HMFG1" @default.
- NCIT_C2541 NCIT_P207 "C0879349" @default.
- NCIT_C2541 NCIT_P322 "GDC" @default.
- NCIT_C2541 NCIT_P329 "43644" @default.
- NCIT_C2541 NCIT_P330 "43644" @default.
- NCIT_C2541 NCIT_P366 "Y_90_Monoclonal_Antibody_HMFG1" @default.
- NCIT_C2541 NCIT_P375 "Y 90 Monoclonal Antibody HMFG1" @default.
- NCIT_C2541 NCIT_P399 "43644" @default.
- NCIT_C2541 normalizedInformationContent "100" @default.
- NCIT_C2541 referenceCount "1" @default.
- NCIT_C2541 hasExactSynonym "MOAB HMFG1, yttrium Y 90" @default.
- NCIT_C2541 hasExactSynonym "Theragyn" @default.
- NCIT_C2541 hasExactSynonym "Y 90 MoAb HMFG1" @default.
- NCIT_C2541 hasExactSynonym "Y 90 Monoclonal Antibody HMFG1" @default.
- NCIT_C2541 hasExactSynonym "Yttrium Y 90 Monoclonal Antibody HMFG1" @default.
- NCIT_C2541 hasExactSynonym "monoclonal antibody HMFG1, yttrium Y 90" @default.
- NCIT_C2541 hasExactSynonym "yttrium Y 90 MOAB HMFG1" @default.
- NCIT_C2541 inSubset NCIT_C128784 @default.
- NCIT_C2541 inSubset NCIT_C157711 @default.
- NCIT_C2541 inSubset NCIT_C157712 @default.
- NCIT_C2541 inSubset NCIT_C176424 @default.
- NCIT_C2541 inSubset NCIT_C177537 @default.
- NCIT_C2541 type Class @default.
- NCIT_C2541 isDefinedBy ncit.owl @default.
- NCIT_C2541 label "Y 90 Monoclonal Antibody HMFG1" @default.
- NCIT_C2541 subClassOf NCIT_C1446 @default.
- NCIT_C2541 subClassOf NCIT_C1511 @default.
- NCIT_C2541 subClassOf NCIT_C1512 @default.
- NCIT_C2541 subClassOf NCIT_C1908 @default.
- NCIT_C2541 subClassOf NCIT_C1909 @default.
- NCIT_C2541 subClassOf NCIT_C2124 @default.
- NCIT_C2541 subClassOf NCIT_C2541 @default.
- NCIT_C2541 subClassOf NCIT_C307 @default.
- NCIT_C2541 subClassOf NCIT_C308 @default.